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Our path starts here

Join us on our journey as we drive scientific research to improve patient treatments for tomorrow.

Cancer

The Institute’s Cancer Center is one of only seven NCI-designated basic cancer research centers in the nation. We couple fundamental biological research with early translational studies to find new, innovative therapies that restore hope to cancer patients and their families.

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Jamey Marth, Ph.D. standing in the lab
Meet a Scientist

Jamey Marth, Ph.D.

Professor, Tumor Microenvironment and Cancer Immunology Program

Dr. Marth's laboratory incorporates biology, engineering, and nanotechnologies to expand biomedical research capabilities.

All Scientists
Garth Powis D. Phil., headshot
Meet a Scientist

Garth Powis, D. Phil.

Jeanne and Gary Herberger Leadership Chair in Cancer Research

Dr. Powis studies the mechanisms that enable cancer cells to survive stress. 

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Francesca Marassi headshot
Meet a Scientist

Francesca Marassi, Ph.D.

Professor, Cancer Metabolism and Signaling Networks Program

Molecules are the building blocks of cellular life. Knowing their structures is key for understanding the basic mechanisms of...

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Immunity

The human immune system is made up of a network of cells, tissues and organs that fight off disease. It can also turn against the body causing autoimmune disorders, such as rheumatoid arthritis, lupus, Crohn’s disease and psoriasis. Increasingly, scientists are learning how to help the body’s immune system to combat cancer. 

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Sumit Chanda profile photo
Meet a Scientist

Sumit Chanda, Ph.D.

Director and Professor, Immunity and Pathogenesis Program

The Chanda lab is interested in unraveling the molecular bases for these complex host-pathogen interactions, which will not only...

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Carl Ware
Meet a Scientist

Carl F. Ware, Ph.D.

Director, Infectious and Inflammatory Diseases Center

Dr. Ware's research is directed at defining the intercellular communication pathways controlling immune responses.

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Neuroscience and Aging

Diseases associated with aging and development are already a leading cause of death and disability, and their prevalence is rising fast—to give one example, by 2050, the number of Alzheimer’s patients age 65 and older may nearly triple from 5 million to 13.8 million.

Learn more

huaxi hu
Meet a Scientist

Huaxi Xu, Ph.D.

Jeanne and Gary Herberger Leadership Chair in Neuroscience Research

Dr. Xu's research efforts focus on understanding the molecular events that underlie the pathogenesis of Alzheimer's Disease.

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Sanford Children's Health Research Center

Genetic diseases in children are rare, and often incurable. Research insights into the genes and environmental factors that play a role in the development of childhood diseases are leading to better ways to more accurately diagnose, treat and cure children with disease.

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Yu Yamaguchi headshot
Meet a Scientist

Yu Yamaguchi, M.D., Ph.D.

Professor, Human Genetics Program

Dr. Yamaguchi's studies the role of proteoglycans and glycosaminoglycans in the context of development and human disorders.

All Scientists
José Luis Millán, Ph.D. headshot
Meet a Scientist

José Luis Millán, Ph.D.

Professor, Human Genetics Program

Dr. Millán works on understanding the mechanisms that control normal skeletal mineralization and elucidating the...

All Scientists
Duc Dong, Ph.D., headshot
Meet a Scientist

Duc Dong, Ph.D.

Associate Dean of Admissions, SBP Graduate School

Dr. Dong’s goal is to uncover fundamental insight into basic and biomedical science through the rigorous investigation of the...

All Scientists
Hudson Freeze, Ph.D. headshot
Meet a Scientist

Hudson Freeze, Ph.D.

Director and Professor, Human Genetics Program

Dr. Freeze’s research focuses on the pathology resulting from faulty glycosylation, the process of adding carbohydrate (sugar)...

All Scientists
Cancer

The Institute’s Cancer Center is one of only seven NCI-designated basic cancer research centers in the nation. We couple fundamental biological research with early translational studies to find new, innovative therapies that restore hope to cancer patients and their families.

Learn more

Garth Powis D. Phil., headshot
Meet a Scientist

Garth Powis, D. Phil.

Jeanne and Gary Herberger Leadership Chair in Cancer Research

Dr. Powis studies the mechanisms that enable cancer cells to survive stress. 

All Scientists
Francesca Marassi headshot
Meet a Scientist

Francesca Marassi, Ph.D.

Professor, Cancer Metabolism and Signaling Networks Program

Molecules are the building blocks of cellular life. Knowing their structures is key for understanding the basic mechanisms of...

All Scientists
Jamey Marth, Ph.D. standing in the lab
Meet a Scientist

Jamey Marth, Ph.D.

Professor, Tumor Microenvironment and Cancer Immunology Program

Dr. Marth's laboratory incorporates biology, engineering, and nanotechnologies to expand biomedical research capabilities.

All Scientists
Immunity

The human immune system is made up of a network of cells, tissues and organs that fight off disease. It can also turn against the body causing autoimmune disorders, such as rheumatoid arthritis, lupus, Crohn’s disease and psoriasis. Increasingly, scientists are learning how to help the body’s immune system to combat cancer. 

Learn more

Carl Ware
Meet a Scientist

Carl F. Ware, Ph.D.

Director, Infectious and Inflammatory Diseases Center

Dr. Ware's research is directed at defining the intercellular communication pathways controlling immune responses.

All Scientists
Sumit Chanda profile photo
Meet a Scientist

Sumit Chanda, Ph.D.

Director and Professor, Immunity and Pathogenesis Program

The Chanda lab is interested in unraveling the molecular bases for these complex host-pathogen interactions, which will not only...

All Scientists
Neuroscience and Aging

Diseases associated with aging and development are already a leading cause of death and disability, and their prevalence is rising fast—to give one example, by 2050, the number of Alzheimer’s patients age 65 and older may nearly triple from 5 million to 13.8 million.

Learn more

huaxi hu
Meet a Scientist

Huaxi Xu, Ph.D.

Jeanne and Gary Herberger Leadership Chair in Neuroscience Research

Dr. Xu's research efforts focus on understanding the molecular events that underlie the pathogenesis of Alzheimer's Disease.

All Scientists
Sanford Children's Health Research Center

Genetic diseases in children are rare, and often incurable. Research insights into the genes and environmental factors that play a role in the development of childhood diseases are leading to better ways to more accurately diagnose, treat and cure children with disease.

Learn more

Duc Dong, Ph.D., headshot
Meet a Scientist

Duc Dong, Ph.D.

Associate Dean of Admissions, SBP Graduate School

Dr. Dong’s goal is to uncover fundamental insight into basic and biomedical science through the rigorous investigation of the...

All Scientists
Hudson Freeze, Ph.D. headshot
Meet a Scientist

Hudson Freeze, Ph.D.

Director and Professor, Human Genetics Program

Dr. Freeze’s research focuses on the pathology resulting from faulty glycosylation, the process of adding carbohydrate (sugar)...

All Scientists
Yu Yamaguchi headshot
Meet a Scientist

Yu Yamaguchi, M.D., Ph.D.

Professor, Human Genetics Program

Dr. Yamaguchi's studies the role of proteoglycans and glycosaminoglycans in the context of development and human disorders.

All Scientists
José Luis Millán, Ph.D. headshot
Meet a Scientist

José Luis Millán, Ph.D.

Professor, Human Genetics Program

Dr. Millán works on understanding the mechanisms that control normal skeletal mineralization and elucidating the...

All Scientists

Drug Discovery and Technology

SBP has the talent and resources to accelerate the development of new therapeutics.

Pebys Center robot arm
Prebys Center

Through development and application of modern drug discovery technologies, SBP is uniquely positioned to make next-generation medicines.

slide in microscope
Shared Resources

Our cores provide advanced technology, expertise and instrumentation to investigators.

scientist and assay plate
Other Platforms

SBP innovates and maintains key technologies and partnerships to facilitate research.

Pebys Center robot arm
Prebys Center

Through development and application of modern drug discovery technologies, SBP is uniquely positioned to make next-generation medicines.

slide in microscope
Shared Resources

Our cores provide advanced technology, expertise and instrumentation to investigators.

Pebys Center robot arm
Other Platforms

SBP innovates and maintains key technologies and partnerships to facilitate research.

SBP Pipeline - Current Projects

SBP Pipeline graphic
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Drug discovery projects

News

cancer cell clusters
Beaker Blog July 16, 2019
Capturing circulating cancer cell clusters using a new microfluidic device
The tool will help scientists understand cancer metastasis, which causes 90% of cancer deaths.
Read more
The Scientist logo
In the News
July 10, 2019
Does the microbiome help the body fight cancer?
The Scientist
San Diego Union-Tribune Logo
In the News
June 28, 2019
Baldness cure on the way? San Diego startup aims to make new hair from stem cells
The San Diego Union-Tribune
Pathways Summer 2019 cover
Donor Magazine June 28, 2019
Pathways Magazine Summer 2019
In this issue of Pathways, you’ll read Waves of Discovery, which describes Dr. Carl Ware’s immunology research and his collaboration with Eli Lilly, which led to a new clinical trial for autoimmune disease. Shaping Immunity discusses Dr. Francesca Marassi’s advances leading to better treatments for antibiotic-resistant infections— one of the biggest public health challenges of our time. In Going for the Goal, we share how Dr. Sumit Chanda’s work toward eliminating HIV has opened new paths to boost the immune system to fight cancer.
Developmental Cell logo
Paper of the Week
EGFR/Pak Signaling Selectively Regulates Glutamine-Deprivation-Induced Macropinocytosis
FierceBiotech logo
In the News
June 27, 2019
Treating pancreatic cancer by starving tumor cells
FierceBiotech
Empty Fuel Gauge
Press Release
June 27, 2019
Nutritional cues regulate pancreatic tumor’s “cell drinking”
Scientists are hopeful that blocking this process could lead to tumor-starving drugs.
Alexey Terskikh, Ph.D.
Press Release
June 27, 2019
Functional hair follicles grown from stem cells
The award-winning science could revolutionize the hair growth industry.
La Jolla Light logo
In the News
June 27, 2019
Grand theft autoimmune
La Jolla Light
Angela Durazo
Beaker Blog June 26, 2019
5 lessons I’ve learned from rheumatoid arthritis and why I’m grateful to scientists who can change my world
Angela Durazo was a rising star triathlete. Then a diagnosis with a autoimmune disorder turned her life upside down.
Read more
Sanford Burnham Prebys Insights:Immunology
Beaker Blog June 26, 2019
An evening with autoimmune disorder experts
Three experts—a scientist, a doctor and a patient—shared their perspective on a single topic: autoimmune disorders.
Read more
Sanford Burnham Prebys Cancer Center Open House poster presentation
Beaker Blog June 20, 2019
Stepping into a scientist’s shoes at the Cancer Center Open House
The San Diego community learned how we’re working to find better ways to combat cancer.
Read more
5.7m

5.7 million Americans are living with Alzheimer’s. By 2050, this number is projected to rise to nearly 14 million. SBP research hopes to change that.

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