COVID-19 Matching Gift Campaign
Every dollar will be matched, so a gift of any amount will help make a difference in the fight against COVID-19.
Thank you to these wonderful donors that have joined us in the fight against COVID-19
- Christopher G. Ayson
- Vivian and Jon Barfield
- Susan and James Blair
- Kathy and Ed Brown
- Carol and Thomas Dillon
- Nancy and James Eastman
- Suzy Fitch
- Marleigh and Alan Gleicher
- Tammy and Lawrence Hershfield
- Informed Prostate Cancer Support Group
- Jean Wickersham and Donald Kearns
- Robert O. Keck
- Joseph Komsky
- Valerie L. Manson
- Wanda L. McCarty
- Josie and James Myers
- Sheri and Steven Spector
- Amy and Jeff Szekeres
In these unprecedented times, Sanford Burnham Prebys scientists are fiercely pursuing research to minimize today’s impact of SARS-CoV-19 and prepare for the pandemics of tomorrow.
Solutions for TODAY
We are in urgent need of medications to treat COVID-19.
Sumit Chanda, Ph.D.
Dr. Chanda has screened thousands of existing, safe drugs to identify those that stop viral replication and could be rapidly be repurposed as a treatment. Thirty drugs that show promise are under further investigation.
Ze’ev Ronai, Ph.D.
Dr. Ronai is studying the interactions between the virus and proteins within our cells. The work is revealing human host cell proteins that may serve as drug targets. His team is also analyzing 18 small molecules that appear to stop the virus from hijacking our cell machinery to make copies of itself.
Alexey Terskikh, Ph.D.
Dr. Terskikh is leading a collaboration with UC San Diego and La Jolla Institute for Immunology to create drug combinations that inhibit the enzymes used to make viral proteins and restore the immune response to levels that inhibit the virus.
Carl Ware, Ph.D.
Severe COVID-19 is linked to an overwhelming inflammatory response—or “cytokine storm”—that can be fatal. Dr. Ware is studying how the virus weakens the immune system and identifying therapeutically active drugs to restore balance and help infected individuals recover.
Planning for TOMORROW
For future pandemics, we’re re-thinking strategy.
Sumit Chanda, Ph.D.
Dr. Chanda is working on broad spectrum antiviral drugs that can be used against a wide variety of respiratory viruses. The Department of Defense has already funded $10M to help provide the nation with safe, effective and innovative therapies
Pam Itkin-Ansari, Ph.D.
Dr. Itkin-Ansari is studying the biological reasons why people with diabetes have a higher risk of severe disease than others. The answers may lead to tailored preventions and treatments.
Evan Snyder, M.D, Ph.D.
Dr. Snyder is testing the effects of drug candidates in human lung “organoids” developed from human stem cells. The work will help us understand how the virus infects and reproduces in lung cells, and can help explain why some infected people fare worse than others.
Conversations with our scientists
Latest news
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How a local La Jolla scientist, Dr. Eva Engvall, helped create the technology that allowed us to do at-home Covid-19 testing -
The new treatment, developed by Avalo Therapeutics with Sanford Burnham Prebys researchers, can mitigate lung damage and improve survival in COVID patients. -
This year’s most popular research stories include scientific breakthroughs in COVID-19, cancer, schizophrenia and more. -
The journal Molecular Cell recently asked Laura Martin-Sancho to share her experience working on SARS-CoV-2 during the pandemic. -
Research pinpoints interferon stimulating genes that control SARS-CoV-2 replication. -
In an effort to find new treatments for COVID-19 that could be made available quickly, researchers searched through FDA-approved drugs to identify candidates that may inhibit SARS-CoV-2 replication. Researchers found that a decades-old anti-leprosy drug exhibits potent antiviral activities against many coronaviruses—including SARS-CoV-2. -
Scientists pointed to clofazimine, a low-cost leprosy drug first approved by the FDA in 1986, as a possible COVID-19 drug after finding promising anti-coronavirus activity in hamsters. -
Phase 2 clinical trial could begin immediately for clofazimine, an FDA-approved drug on WHO’s List of Essential Medicines. -
Tom Brock started the research that would go on to revolutionize the field of biology – and pave the road to the development of the gold-standard COVID-19 tests used to fight a pandemic – with a question. -
Physician-scientist Evan Snyder spent two weeks in a gymnasium-turned ICU caring for people with severe COVID-19. -
'Immune cop': La Jolla scientists identify the lungs’ sensor that detects virus that causes COVID-19
Sumit Chanda led a study that found the sensor in human lungs that detects SARS-CoV-2, the virus that causes COVID-19. -
Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified the sensor in human lungs that detects SARS-CoV-2 and signals that it’s time to mount an antiviral response. -
Read about our progress in the fight against COVID-19, insights into treating deadly cancers, research that may help children born with a rare condition, and more. -
To learn what scientists know so far about COVID-19 and its effect on the brain, we caught up with Anne Bang, Ph.D., director of Cell Biology at Sanford Burnham Prebys’ Conrad Prebys Center for Chemical Genomics. -
The world may see two coronavirus vaccines before the end of the year. Dr. Carl Ware may have already received a dose. -
As coronavirus cases surge across the country, topping out at a million new cases in less than a week, there’s at least some promising news. -
Our leading COVID-19 researchers give their take on the Pfizer vaccine -
After a career of exploring how viruses wreak havoc on our health, researcher now becomes a “subject” in a vaccine study. -
Bioinformatics platform simplifies data analysis to help biologists glean scientific insights into the novel coronavirus as body of data surges. -
Scientists will study how SARS-CoV-19 hijacks the immune system and creates a “cytokine storm” -
We asked 16 locals—from students to nurses, hoteliers and store owners—how they're working through the pandemic and helping others.
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Researchers are hoping the study shows how coronavirus affects people from different backgrounds.
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Multiple drugs improve the activity of remdesivir, a current standard-of-care treatment for COVID-19 -
The research team will test two existing drugs against “mini lungs in a dish” that have been infected with SARS-CoV-2. -
Neutralizing antibodies have the potential for both prevention and treatment of COVID-19. -
Long-time supporter Dinah Conyers Ruch discusses the impact of giving to biomedical research—especially COVID-19 efforts. -
Our namesake shares why supporting biomedical research is more important than ever before. -
San Diego scientists are using "mini lungs" to understand how COVID-19 impacts the lungs of people with varying backgrounds and conditions. -
In just three months, international researchers working together found 30 already existing drugs that seem to stop the coronavirus from destroying human cells. -
Driven by the pandemic’s spread, research teams have been screening thousands of drugs to see if they have this unexpected potential to fight the coronavirus. -
A local research institute says it has discovered 30 promising potential treatments for the COVID-19 coronavirus and aims to have them available for trial soon.
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While San Diego County doctors and nurses fight COVID-19 on the front lines in hospital emergency rooms and intensive care units, scientists and researchers here are looking for answers. -
Evan Snyder tells us how he is using lung organoids to find effective treatments for COVID-19. -
Working with renown research labs across the world, San Diego based Sanford Burnham Prebys Medical Discovery Institute is leading the charge to find new therapies to treat COVID-19 patients.
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An online survey reveals bottlenecks and challenges and barriers faced by more than 1,700 biology labs. -
Sumit Chanda, Ph.D. discusses the findings from his SARS-CoV-2 drug screen. -
San Diego scientists have uncovered more than two dozen potential antiviral treatments for COVID-19. The discovery is a first step in finding a cure for the deadly novel coronavirus.
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“Between now and us getting a vaccine, this is our best hope," Dr. Sumit Chanda said.
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Four drugs hold near-term promise to fight the novel coronavirus. -
Researchers are combing through currently approved drugs as well as taking creative risks by investigating never-before-tried therapies to combat this coronavirus. Here are the most promising so far. -
This is the biggest uprising by local scientists since the AIDS crisis...The Union-Tribune turned to 10 scientists to find out what they’re doing, precisely when they realized how bad things might get, and how the pandemic is affecting them personally. -
The next step for the drugs that displayed progressive results is to move forward to clinical testing.
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Speed, efficacy and safety are the primary concerns of researchers searching for treatments. -
Infectious disease expert Sumit Chanda tells us how his team is combating the virus, and the advice he gives his loved ones. -
Here’s what Sumit Chanda, Ph.D., director of Sanford Burnham Prebys’ Immunity and Pathogenesis Program, has to say about the virus spreading fear around the world.
