# Sanford Burnham Prebys

> Sanford Burnham Prebys is dedicated to pushing biomedical discoveries faster and further toward clinical treatment and therapies that improve human lives\.

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## Pages
- [Philanthropy \- Past Events](https://sbpdiscovery.org/philanthropy/past-events/)
- [Publications](https://sbpdiscovery.org/about/publications/)
- [Our Community](https://sbpdiscovery.org/about/our-community/)
- [Our History](https://sbpdiscovery.org/about/our-history/): The history of Sanford Burnham Prebys, from its founding in 1976 by William and Lillian to today\.
- [Learning \& Development Quarterly](https://sbpdiscovery.org/education/ld-quarterly/): Our quarterly newsletter focuses on graduate education, postdoctoral training, and international services at Sanford Burnham Prebys\.

## Posts
- [Women in Science Lecture series spotlights structural biology and immunology leader](https://sbpdiscovery.org/women-in-science-lecture-series-spotlights-structural-biology-and-immunology-leader/): The series highlights the groundbreaking work and unique perspectives of women leaders in the biomedical sciences\.
- [David A\. Brenner appears on nation's longest running community podcast](https://sbpdiscovery.org/brenner-appears-on-nations-longest-running-community-podcast/): David Brenner, MD, appeared on the podcast to discuss the mission of the Institute, its research collaborations, the role of AI and the current state of biomedical research locally and beyond\.
- [Science in Pictures](https://sbpdiscovery.org/science-in-pictures-apr6-26/): A weekly image series featuring selected pictures in science • Blood clot
- [Science in Pictures](https://sbpdiscovery.org/science-in-pictures-apr-13-26/): A weekly image series featuring selected pictures in science • Vibrio bacteria
- [Science in Pictures](https://sbpdiscovery.org/science-in-pictures-apr-20-26/): A weekly image series featuring selected pictures in science • Zebrafish neural tube

## Scientists
- [Michael Jackson, PhD](https://sbpdiscovery.org/scientists/michael-jackson-phd/)
- [Ahmed Mahmoud, PhD](https://sbpdiscovery.org/scientists/ahmed-mahmoud-phd/)
- [Rolf Bodmer, PhD](https://sbpdiscovery.org/scientists/rolf-bodmer-phd/)
- [Sanjeev S\. Ranade, PhD](https://sbpdiscovery.org/scientists/sanjeev-s-ranade-phd/)
- [Yuk\-Lap \(Kevin\) Yip, PhD](https://sbpdiscovery.org/scientists/yuk-lap-kevin-yip-phd/)

## Labs
- [Karin Lab](https://sbpdiscovery.org/labs/karin-lab/): In the Tharp lab, we aim to understand how cells regulate and utilize metabolic programs to adapt to different microenvironments\. Our main goal is to develop therapeutics that prevent cancer cells from metastasizing \- by interfering with their ability to tune their metabolism to survive in secondary sites\.
- [Tharp Lab files](https://sbpdiscovery.org/labs/tharp-lab-files/): In the Tharp lab, we aim to understand how cells regulate and utilize metabolic programs to adapt to different microenvironments\. Our main goal is to develop therapeutics that prevent cancer cells from metastasizing \- by interfering with their ability to tune their metabolism to survive in secondary sites\.
- [Tharp Lab](https://sbpdiscovery.org/labs/tharp-lab/): In the Tharp lab, we aim to understand how cells regulate and utilize metabolic programs to adapt to different microenvironments\. Our main goal is to develop therapeutics that prevent cancer cells from metastasizing \- by interfering with their ability to tune their metabolism to survive in secondary sites\.
- [Marth Lab](https://sbpdiscovery.org/labs/marth-lab/)
- [Bradley Lab](https://sbpdiscovery.org/labs/bradley-lab/): The Bradley Lab is focused on understanding the regulation of T lymphocytes in virus infections where the immune response results in viral clearance and the development of immunologic memory, and in chronic virus infections where the ongoing immune response leads to viral persistence and immune dysregulation\.

## Events
- [Peering Inside: Cardiac interoception neural networks governing physiology and behavior in health and disease »](https://sbpdiscovery.org/events/peering-inside-cardiac-interoceptive-neural-networks-governing-physiology-and-behavior-in-health-and-disease/): Distinguished Cardiovascular and Muscular Diseases Seminar Series: Vineet Augustine, PhD, UC San Diego
- [Cellular recycling in aging and disease – the importance of taking out the trash »](https://sbpdiscovery.org/events/cellular-recycling-in-aging-and-disease-the-importance-of-taking-out-the-trash-2/): Distinguished Cardiovascular and Muscular Diseases Seminar Series: Malene Hansen, PhD, The Buck Institute
- [Community Outreach Symposium »](https://sbpdiscovery.org/events/sbp-sn-outreach-symposium/): The Community Outreach Symposium at Sanford Burnham Prebys is a free community event that gives postdocs and graduate students a platform to sharpen their science communication skills\.
- [50 Years of Discovery Mini Symposium »](https://sbpdiscovery.org/events/50-years-of-discovery-mini-symposium/): In celebration of the Institute's milestone anniversary, we will reflect on our past, honor those who shaped our story, and look ahead to the next 50 years\.
- [Discovery Series: Inside the Science of Heart Disease »](https://sbpdiscovery.org/events/inside-the-science-of-heart-disease/): Our Discovery Series program offers a behind\-the\-scenes look at cardiovascular research at Sanford Burnham Prebys Medical Discovery Institute\. The presentation will explore how scientists are advancing the understanding of heart disease and translating discovery into potential therapies\.

## Leadership
- [Jeannine Zuber](https://sbpdiscovery.org/leadership/jeannine-zuber/)
- [Lauren Mitchell](https://sbpdiscovery.org/leadership/lauren-mitchell/)
- [Amy Marone](https://sbpdiscovery.org/leadership/amy-marone/)
- [Stan Coleman](https://sbpdiscovery.org/leadership/stan-coleman/)
- [Diane Klotz, PhD](https://sbpdiscovery.org/leadership/diane-klotz-phd/)

## Trustees
- [Stuart A\. Tanz](https://sbpdiscovery.org/trustees/stuart-a-tanz/)
- [David L\. Szekeres](https://sbpdiscovery.org/trustees/david-l-szekeres/)
- [Lonna J\. Williams Stolper](https://sbpdiscovery.org/trustees/lonna-j-williams-stolper/)
- [Ted Roth](https://sbpdiscovery.org/trustees/ted-roth/)
- [William A\. Roper](https://sbpdiscovery.org/trustees/william-a-roper/)

## Featured Articles
- [RNA isoform diversity, splicing variants and switching in single cells of the Alzheimer’s disease brain](https://sbpdiscovery.org/paper-of-the-week/rna-isoform-diversity-splicing-variants-and-switching-in-single-cells-of-the-alzheimers-disease-brain/)
- [Synthesis and Characterization of ULK1/2 Kinase Inhibitors That Inhibit Autophagy and Upregulate Expression of Major Histocompatibility Complex I for the Treatment of Non\-Small Cell Lung Cancer](https://sbpdiscovery.org/paper-of-the-week/synthesis-and-characterization-of-ulk1-2-kinase-inhibitors-that-inhibit-autophagy-and-upregulate-expression-of-major-histocompatibility-complex-i-for-the-treatment-of-non-small-cell-lung-cancer/)
- [Tissue morphology predicts telomere shortening in human tissues](https://sbpdiscovery.org/paper-of-the-week/tissue-morphology-predicts-telomere-shortening-in-human-tissues/)
- [Smac mimetic combined with eCD4\-Ig reverses latency without reducing SHIV reservoirs in rhesus macaques](https://sbpdiscovery.org/paper-of-the-week/smac-mimetic-combined-with-ecd4-ig-reverses-latency-without-reducing-shiv-reservoirs-in-rhesus-macaques/)
- [SAKURA: a knowledge\-guided approach to recovering important, rare signals from single\-cell data](https://sbpdiscovery.org/paper-of-the-week/sakura-a-knowledge-guided-approach-to-recovering-important-rare-signals-from-single-cell-data/)

## Press Releases
- [Cholesterol\-craving cancers need lipid enzymes to use metabolites for growth](https://sbpdiscovery.org/press/cholesterol-craving-cancers-need-lipid-enzymes-to-use-metabolites-for-growth/): Study from the Emerling lab finds kinases move cholesterol in the cell to where it can activate a growth pathway in many aggressive cancers\.
- [Qualcomm co\-founder Andrew Viterbi gives $5 million to Sanford Burnham Prebys Medical Discovery Institute to advance AI\-powered research](https://sbpdiscovery.org/press/qualcomm-co-founder-andrew-viterbi-gives-5-million-to-sanford-burnham-prebys-medical-discovery-institute-to-advance-ai-powered-research/): The $5 million gift will endow the Andrew and Erna Viterbi Distinguished Chair in the Center for Data Science and Artificial Intelligence\.
- [Sanford Burnham Prebys Awarded $3\.9 Million NIH Grant to Develop First\-in\-Class Non\-Opioid Pain Treatment](https://sbpdiscovery.org/press/sanford-burnham-prebys-awarded-3-9-million-nih-grant-to-develop-first-in-class-non-opioid-pain-treatment/): The NINDS has awarded a $3\.9 million grant to a multi\-institutional team led to develop a non\-opioid pain therapeutic and advance it into a Phase 1 clinical trial\.
- [Anne Bang joins $13M research project on age\-related RNA pollution and brain degeneration](https://sbpdiscovery.org/press/anne-bang-joins-13m-research-project-on-age-related-rna-pollution-and-brain-degeneration/): The project’s San Diego\-based research team is funded by the California Institute for Regenerative Medicine\.
- [Sanford Burnham Prebys welcomes two new members to its board of directors](https://sbpdiscovery.org/press/sanford-burnham-prebys-welcomes-two-new-members-to-its-board-of-directors/): Sanford Burnham Prebys has added two new and distinguished members to its Board of Directors: Sheri L\. Jamieson and Neil Davis Wachsberger\.

## Magazines
- [Winter 2016](https://sbpdiscovery.org/magazine/winter-2016/)
- [Summer 2016](https://sbpdiscovery.org/magazine/summer-2016/)
- [Summer 2017](https://sbpdiscovery.org/magazine/summer-2017/)
- [Summer 2018](https://sbpdiscovery.org/magazine/summer-2018/)
- [Summer 2011](https://sbpdiscovery.org/magazine/summer-2011/)

## Science 101 Articles
- [Science 101: Breast cancer](https://sbpdiscovery.org/science-101/science-101-breast-cancer/)
- [Science 101: Cell signaling](https://sbpdiscovery.org/science-101/science-101-cell-signaling/)
- [Science 101: Addiction](https://sbpdiscovery.org/science-101/science-101-addiction/)
- [Science 101: Stem cells](https://sbpdiscovery.org/science-101/science-101-stem-cells/): Stem cells are the earliest type of cell, found in both embryonic and adult organisms\. Through differentiation, they can become virtually any type of cell in the human body\.
- [Science 101: Alzheimer’s disease](https://sbpdiscovery.org/science-101/science-101-alzheimers-disease/)

## Categories
- [Uncategorized](https://sbpdiscovery.org/category/uncategorized/)
- [Research News](https://sbpdiscovery.org/category/researchnews/)
- [What's Happening](https://sbpdiscovery.org/category/whatshappening/)
- [People](https://sbpdiscovery.org/category/people/)
- [Workforce Engagement and Belonging](https://sbpdiscovery.org/category/workforce-engagement-belonging/)

## Tags
- [Cancer Center](https://sbpdiscovery.org/tag/cancercenter/)
- [NIH funding](https://sbpdiscovery.org/tag/nihfunding/)
- [cancer](https://sbpdiscovery.org/tag/cancer/)
- [grants](https://sbpdiscovery.org/tag/grants/)
- [Science in Pictures](https://sbpdiscovery.org/tag/scienceinpictures/)

## Faculty Types
- [Faculty](https://sbpdiscovery.org/faculty-type/faculty/)
- [Staff](https://sbpdiscovery.org/faculty-type/staff/)
- [Emeritus Faculty](https://sbpdiscovery.org/faculty-type/emeritus-faculty/)
- [Research Faculty](https://sbpdiscovery.org/faculty-type/research-faculty/)
- [Adjunct Faculty](https://sbpdiscovery.org/faculty-type/adjunct-faculty/)

##  Positions
- [Member](https://sbpdiscovery.org/scientist-position/member/)
- [Professor](https://sbpdiscovery.org/scientist-position/professor/)
- [Assistant Professor](https://sbpdiscovery.org/scientist-position/assistant-professor/)
- [Director](https://sbpdiscovery.org/scientist-position/director/)
- [Associate Professor](https://sbpdiscovery.org/scientist-position/associate-professor/)

## Related Diseases
- [Cancer](https://sbpdiscovery.org/related-diseases/cancer/)
- [Breast Cancer](https://sbpdiscovery.org/related-diseases/breast-cancer/)
- [Alzheimer's Disease](https://sbpdiscovery.org/related-diseases/alzheimers-disease/)
- [Aging\-Related Diseases](https://sbpdiscovery.org/related-diseases/aging-related-diseases/)
- [Neurodegenerative and Neuromuscular Diseases](https://sbpdiscovery.org/related-diseases/neurodegenerative-and-neuromuscular-diseases/)

## Phenomena or Processes
- [Cell Signaling](https://sbpdiscovery.org/phenomena-processes/cell-signaling/)
- [Cell Biology](https://sbpdiscovery.org/phenomena-processes/cell-biology/)
- [Inflammation](https://sbpdiscovery.org/phenomena-processes/inflammation/)
- [Aging](https://sbpdiscovery.org/phenomena-processes/aging/)
- [Cancer Biology](https://sbpdiscovery.org/phenomena-processes/cancer-biology/)

## Anatomical Systems and Sites
- [Immune System and Inflammation](https://sbpdiscovery.org/anatomical-system-site/immune-system-and-inflammation/)
- [Brain](https://sbpdiscovery.org/anatomical-system-site/brain/)
- [General Cell Biology](https://sbpdiscovery.org/anatomical-system-site/general-cell-biology/)
- [Nervous System](https://sbpdiscovery.org/anatomical-system-site/nervous-system/)
- [Vasculature](https://sbpdiscovery.org/anatomical-system-site/vasculature/)

## Research Models
- [Mouse](https://sbpdiscovery.org/research-models/mouse/)
- [Human Cell Lines](https://sbpdiscovery.org/research-models/human-cell-lines/)
- [Mouse Cell Lines](https://sbpdiscovery.org/research-models/mouse-cell-lines/)
- [Primary Human Cells](https://sbpdiscovery.org/research-models/primary-human-cells/)
- [Primary Cells](https://sbpdiscovery.org/research-models/primary-cells/)

## Techniques and Technologies
- [Cellular and Molecular Imaging](https://sbpdiscovery.org/techniques-technologies/cellular-and-molecular-imaging/)
- [Bioinformatics](https://sbpdiscovery.org/techniques-technologies/bioinformatics/)
- [Drug Discovery](https://sbpdiscovery.org/techniques-technologies/drug-discovery/)
- [Fluorescence Microscopy](https://sbpdiscovery.org/techniques-technologies/fluorescence-microscopy/)
- [Gene Expression](https://sbpdiscovery.org/techniques-technologies/gene-expression/)

## Leadership Types
- [Board of Directors](https://sbpdiscovery.org/leadership-type/board-of-directors/)
- [Administrative](https://sbpdiscovery.org/leadership-type/administrative/)
- [Scientific](https://sbpdiscovery.org/leadership-type/scientific/)
- [Management](https://sbpdiscovery.org/leadership-type/management/)
- [Scientific Advisory Board](https://sbpdiscovery.org/leadership-type/sab/)

## Page Types
- [Shared Resource](https://sbpdiscovery.org/page-type/shared-resource/)
- [Tribute](https://sbpdiscovery.org/page-type/tribute/)
- [Center](https://sbpdiscovery.org/page-type/center/)
- [Theme](https://sbpdiscovery.org/page-type/theme/)
- [Program](https://sbpdiscovery.org/page-type/program/)

## Event Types
- [Seminar](https://sbpdiscovery.org/event-type/seminar/)
- [Symposium](https://sbpdiscovery.org/event-type/symposium/)
- [Community Forum](https://sbpdiscovery.org/event-type/community-forum/)
- [Other](https://sbpdiscovery.org/event-type/other/)

## Event Categories
- [Cancer Center Seminar Series](https://sbpdiscovery.org/event-category/cancer-center-seminar-series/)
- [DEIB](https://sbpdiscovery.org/event-category/deib/)

## Optional
- [Sitemap index](https://sbpdiscovery.org/sitemap_index.xml)