San Diego Nathan Shock Center - Sanford Burnham Prebys

San Diego Nathan Shock Center

San Diego Nathan Shock Center

Established in 2020 with funding from the National Institute of Aging, part of the National Institutes of Health, the San Diego Nathan Shock Center of Excellence in the Basic Biology of Aging is a consortium of Sanford Burnham Prebys, Salk Institute for Biological Studies and the University of California San Diego. 

The center focuses on the heterogeneity of aging, the fact that cells, organs and people age at different rates and that this “biological age” is a better indicator of an individual’s susceptibility to age-related declines and diseases.

The center provides resources to scientist-members to develop new human cell models of aging, enabling deeper analyses of molecular, cellular and tissue heterogeneity and support of basic biology of aging research through development, training and mentoring activities.

Recent Publications

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Bi-allelic UGGT1 variants cause a congenital disorder of glycosylation.

Dardas Z, Harrold L, Calame DG, Salter CG, Kikuma T, Guay KP, Ng BG, Sano K, Saad AK, Du H, Sangermano R, Patankar SG, Jhangiani SN, Gürsoy S, Abdel-Hamid MS, Ahmed MKH, Maroofian R, Kaiyrzhanov R, Salayev K, Jones WD, Pérez Caballero A, McGavin L, Spiller M, Durkie M, Wood N, O’Grady L, Goldenberg P, Neumeyer AM, Begtrup A, Abdel-Ghafar SF, Zaki MS, Van Esch H, Posey JE, Wenger OK, Scott EM, Bujakowska KM, Gibbs RA, Pehlivan D, Marafi D, Leslie JS, Ubeyratna N, Day J, Owens M, Settle J, Balkhy S, Tamim A, Alabdi L, Alkuraya FS, Takeda Y, Freeze HH, Hebert DN, Lupski JR, Crosby AH, Baple EL

Am J Hum Genet 2025 Apr 19 ;():
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