Malene Hansen, PhD, associate professor in our Development, Aging, and Regeneration Program has been awarded the Julie Martin Mid-Career Award in Aging Research. The award includes a new grant to continue her research in the field of aging. Hansen is a three-time American Federation for Aging Research (AFAR) grant recipient. AFAR’s grants are given to scientists at institutions nationwide based on hard work, ingenuity, and leadership that advance cutting-edge research to help us live healthier, longer lives. Continue reading “Sanford-Burnham researcher awarded American Federation for Aging Research award”
Category: Development, Aging and Regeneration
Why people with Down syndrome invariably develop Alzheimer’s disease
A new study by researchers at Sanford-Burnham reveals the process that leads to changes in the brains of individuals with Down syndrome—the same changes that cause dementia in Alzheimer’s patients. The findings, published in Cell Reports, have important implications for the development of treatments that can prevent damage in neuronal connectivity and brain function in Down syndrome and other neurodevelopmental and neurodegenerative conditions, including Alzheimer’s disease. Continue reading “Why people with Down syndrome invariably develop Alzheimer’s disease”
New insights into how the heart forms may help identify heart defects
This is a post by our guest writer Janelle Weaver, PhD
The formation of the heart during development is a highly complex process that requires precise coordination between cells and molecular signaling pathways. The fruit fly has been widely used for studying the underlying cellular and molecular mechanisms, and a great deal is known about how the fate of heart cells is controlled by signaling pathways and transcription factors—proteins that control gene activity. But beyond that, events that regulate heart formation have not been clear. Continue reading “New insights into how the heart forms may help identify heart defects”
Researchers discover a key to making new muscles
Researchers at Sanford-Burnham have developed a novel technique to promote tissue repair in damaged muscles. The technique also creates a sustainable pool of muscle stem cells needed to support multiple rounds of muscle repair. The study, published on September 7 in Nature Medicine, provides promise for a new therapeutic approach to treating the millions of people suffering from muscle diseases, including those with muscular dystrophies and muscle wasting associated with cancer and aging. Continue reading “Researchers discover a key to making new muscles”