Center for Therapeutics Discovery

Science Becomes Progress

Fundamental to the mission of Sanford Burnham Prebys is the translation of academic research into actionable drug discovery for the development of new therapeutics to remedy our most debilitating diseases.

The Center for Therapeutics Discovery (CTD) is where it happens, where the rubber meets the road and concepts become realities.

We use physical and computational screening to identify prototype drugs, then develop these into first-in-class therapeutics through medicinal chemistry-led optimization.

We deploy the latest technologies, including robotically enabled high-throughput screening, assay development, in vitro and in vivo pharmacology, medicinal and computational chemistry and cheminformatics — all enabled and enhanced by artificial intelligence and machine learning.

Concepts for these novel therapeutics originate with Sanford Burnham Prebys faculty and collaborators. Scientists at CTD translate these ideas and insights into actual drugs, primarily small molecule chemicals that comprise 90% of pharmaceutical drugs, typically administered as pills to patients

Conrad Prebys Center for Chemical Genomics

From target validation to preclinical development, our ultramodern technologies accelerate pharmaceutical discovery, helping researchers rapidly identify and develop new molecules and compounds for next-generation drugs.

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