Diabetes and Obesity Archives - Page 2 of 2 - Sanford Burnham Prebys

Category: Diabetes and Obesity

Institute News

Exercise following bariatric surgery provides health benefits

Authorsgammon
Date

December 1, 2014

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A new study by researchers at the Florida Hospital – Sanford-Burnham Translational Research Institute for Metabolism and Diabetes (TRI-MD) in Orlando, Fla., shows that patients who moderately exercise after bariatric surgery (weight-loss surgery) gain additional health improvements in glucose metabolism and cardiorespiratory fitness compared to patients who lead a sedentary lifestyle after surgery. The findings confirm the physiological and potential clinical benefits of adding an exercise regime following weight-loss surgery. Continue reading “Exercise following bariatric surgery provides health benefits”

Institute News

Sanford-Burnham’s Steven R. Smith leads clinical study on new weight-loss treatment

Authorsgammon
Date

November 3, 2014

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In a new pilot study led by principal investigator Steven R. Smith, MD, the weight-loss drug lorcaserin (LOR), was tested in combination with the drug phentermine (phen) to compare safety and weight loss to administration of LOR alone. The results showed that the combination of drugs more than doubled weight loss achieved compared to LOR alone, and that treatment with LOR plus phen was not associated with any additional adverse events compared either drug alone. Continue reading “Sanford-Burnham’s Steven R. Smith leads clinical study on new weight-loss treatment”

Institute News

Sanford-Burnham welcomes two new scientists to Lake Nona

Authorpbartosch
Date

October 29, 2014

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We’re excited to announce that we have recruited two cardiometabolic experts to our Medical City campus in Lake Nona (Orlando), Fla. Peter A. Crawford, MD, PhD, and Andre d’Avignon, PhD, join our Cardiovascular Pathobiology Program from Washington University in St. Louis, Mo. The increasing density of local scientists and clinicians in Orlando is accelerating the growth of the region’s bio-medical industry, promoting both economic development and the quality of health care. Continue reading “Sanford-Burnham welcomes two new scientists to Lake Nona”

Institute News

A new way to generate insulin-producing cells in type 1 diabetes

Authorsgammon
Date

July 31, 2014

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A new study by researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) has found that a peptide called caerulein can convert existing cells in the pancreas into those cells destroyed in type 1 diabetes—insulin-producing beta cells. The study, published online July 31 in Cell Death and Disease, suggests a new approach to treating the estimated 3 million people in the U.S., and over 300 million worldwide, living with type 1 diabetes. Continue reading “A new way to generate insulin-producing cells in type 1 diabetes”

Institute News

A new link between obesity, inflammation, and insulin resistance

Authorsgammon
Date

July 17, 2014

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A new study by researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) has identified a new signal that triggers the events leading to insulin resistance in obesity. The signal causes inflammation in adipose tissue and leads to metabolic disease. The study, published July 17 in Cell Metabolism, suggests that blocking this signal may protect against the development of metabolic disease, type 2 diabetes, and other disorders caused by obesity-linked inflammation. Continue reading “A new link between obesity, inflammation, and insulin resistance”

Institute News

Genes promote hardening of arteries in type 2 diabetes

Authorsgammon
Date

July 15, 2014

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Type 2 diabetes has become a national epidemic, affecting nearly 26 million children and adults in the U.S. and approximately 170 million worldwide. According to the American Diabetes Association, $245 billion in costs are associated with diabetes, and 1 in 5 health-care dollars is spent caring for diabetics. A significant portion of the health costs associated with diabetes are those attributed to complications of the disease—including heart attacks, heart failure, stroke, dementia, chronic kidney disease, and amputations of the lower limbs. These complications emerge partly from hardening of the arteries caused by calcium deposits—a process known as arterial calcification—and are much more common in type 2 diabetics than in non-diabetics. Continue reading “Genes promote hardening of arteries in type 2 diabetes”