Unleashing the cancer-fighting gene TP53 in leukemia with a novel combination treatment

Combining MDM2 and BET inhibition produces a "double whammy" effect in acute myeloid leukemia by activating p53 via two different pathways, a new study found.

'Immune cop': La Jolla scientists identify the lungs’ sensor that detects virus that causes COVID-19

Sumit Chanda led a study that found the sensor in human lungs that detects SARS-CoV-2, the virus that causes COVID-19.

Astronauts experience these key changes in space that could impact their health, new research shows

"For the first time, we can see the cellular and molecular changes that may underlie the heart conditions seen in astronaut studies," said Karen Ocorr, co-senior author of the study.

Research reveals why some tumors have different makeup of cells

Molecular changes in cells called fibroblasts may explain why one type of colon cancer doesn’t respond to therapy, according to a new study by Drs. Jorge Moscat-Guillen and Maria Diaz-Meco, adjunct professors at Sanford Burnham Prebys.

Moderna Vaccine Around 95% Effective Shows Promise For End Of COVID-19 Pandemic

As coronavirus cases surge across the country, topping out at a million new cases in less than a week, there’s at least some promising news.