Opinion: Rare diseases affect 30 million Americans. These are the challenges to find their cure.

Rare diseases are conditions that afflict less than 200,000 people in the United States, but they are far less rare in the aggregate, afflicting millions—and in their disparate types: There are more than 10,000 known rare diseases. In his latest essay in the UT, David Brenner discusses the particular challenges of identifying and developing treatments for rare diseases, and the work being done at the Sanford Children’s Health Research Center.

Opinion: Science is advancing past the need for drug testing on animals. Let’s embrace alternatives.

In David Brenner’s latest essay in the San Diego Union-Tribune, he describes how technological advances, from complex cell cultures and organoids to computational models driven by artificial intelligence are increasingly lessening the need to rely upon problematic animal testing for new drugs and therapies – and why they are more likely to directly and effectively inform research and future success.

Opinion: Matthew Perry was open about addiction. Like him, we can’t stop trying to overcome it.

David Brenner’s essay “Opinion: Matthew Perry was open about addiction. Like him, we can’t stop trying to overcome it,” is now available through the San Diego Union-Tribune’s Community Voices Project. The monthly column is a forum for respectful discourse about news of the day and matters of the community that brings thought leaders together in a public dialogue, which can be a model for others.

Sanford Burnham Prebys gala celebrates scientific recruitment after $70 million gift

The Sanford Burnham Prebys medical research institute in La Jolla held a gala called “A Future Filled With Discoveries and Cures” on Oct. 21 at the Estancia La Jolla Hotel & Spa to extoll its recruitment of “the very best scientists from the best labs at the best institutions in the world.”

Regrowing Damaged Nerves by Targeting Aging Enzyme

Researchers at Stanford University School of Medicine and Sanford Burnham Prebys have discovered that targeting an enzyme associated with aging after nerve injury in a mouse model with a small molecule inhibitor, promoted regeneration of motor nerve and formation of neuromuscular synapses that resulted in accelerated recovery of strength.