Boosting immunotherapy in aggressive brain cancer

By deactivating the cells that sustain tumors, researchers from Sanford Burnham Prebys are working to treat one of the deadliest brain cancers.

How a breast cancer advocate shapes research at Sanford Burnham Prebys

Svasti Haricharan, a Sanford Burnham Prebys assistant professor and Karen McDonald, an advocate working with Svasti's team, discuss how to include patient voices in the biomedical research process.

How misplaced DNA contributes to chronic illness

Researchers from Sanford Burnham Prebys recently published a review article in the journal Cell about cytoplasmic DNA. This is DNA that has migrated outside of the nucleus, which can act as a short-term protective strategy against cancer formation. However, the DNA can also contribute to cancer development through chronic inflammation over the long term.

This enzyme is one of the hardest working proteins in the body

Researchers led by Yu Yamaguchi, M.D., Ph.D., have shown that in the absence of a certain protein, levels of an important carbohydrate increase to up to 40 times their usual level.