Lars Pache's Research Focus
Faculty Mentor: Sumit Chanda, Ph.D.
Lars Pache's Bio
Publications
HIV-1 Vpu is a potent transcriptional suppressor of NF-κB-elicited antiviral immune responses.
Langer S, Hammer C, Hopfensperger K, Klein L, Hotter D, De Jesus PD, Herbert KM, Pache L, Smith N, van der Merwe JA, Chanda SK, Fellay J, Kirchhoff F, Sauter D
Elife 2019 Feb 5 ;8
Transcription Elongation Can Affect Genome 3D Structure.
Heinz S, Texari L, Hayes MGB, Urbanowski M, Chang MW, Givarkes N, Rialdi A, White KM, Albrecht RA, Pache L, Marazzi I, García-Sastre A, Shaw ML, Benner C
Cell 2018 Sep 6 ;174(6):1522-1536.e22
Large-Scale Arrayed Analysis of Protein Degradation Reveals Cellular Targets for HIV-1 Vpu.
Jain P, Boso G, Langer S, Soonthornvacharin S, De Jesus PD, Nguyen Q, Olivieri KC, Portillo AJ, Yoh SM, Pache L, Chanda SK
Cell Rep 2018 Feb 27 ;22(9):2493-2503
Metascape provides a biologist-oriented resource for the analysis of systems-level datasets.
Zhou Y, Zhou B, Pache L, Chang M, Khodabakhshi AH, Tanaseichuk O, Benner C, Chanda SK
Nat Commun 2019 Apr 3 ;10(1):1523
HIV-1 Vpu is a potent transcriptional suppressor of NF-κB-elicited antiviral immune responses.
Langer S, Hammer C, Hopfensperger K, Klein L, Hotter D, De Jesus PD, Herbert KM, Pache L, Smith N, van der Merwe JA, Chanda SK, Fellay J, Kirchhoff F, Sauter D
Elife 2019 Feb 5 ;8
Transcription Elongation Can Affect Genome 3D Structure.
Heinz S, Texari L, Hayes MGB, Urbanowski M, Chang MW, Givarkes N, Rialdi A, White KM, Albrecht RA, Pache L, Marazzi I, García-Sastre A, Shaw ML, Benner C
Cell 2018 Sep 6 ;174(6):1522-1536.e22
Author Correction: SMARCA2-regulated host cell factors are required for MxA restriction of influenza A viruses.
Dornfeld D, Dudek AH, Vausselin T, Günther SC, Hultquist JF, Giese S, Khokhlova-Cubberley D, Chew YC, Pache L, Krogan NJ, Garcia-Sastre A, Schwemmle M, Shaw ML
Sci Rep 2018 May 14 ;8(1):7782
Large-Scale Arrayed Analysis of Protein Degradation Reveals Cellular Targets for HIV-1 Vpu.
Jain P, Boso G, Langer S, Soonthornvacharin S, De Jesus PD, Nguyen Q, Olivieri KC, Portillo AJ, Yoh SM, Pache L, Chanda SK
Cell Rep 2018 Feb 27 ;22(9):2493-2503
SMARCA2-regulated host cell factors are required for MxA restriction of influenza A viruses.
Dornfeld D, Dudek AH, Vausselin T, Günther SC, Hultquist JF, Giese S, Khokhlova-Cubberley D, Chew YC, Pache L, Krogan NJ, Garcia-Sastre A, Schwemmle M, Shaw ML
Sci Rep 2018 Feb 1 ;8(1):2092