Addiction is perhaps the most and least visible of public health crises in the United States. Tens of millions of Americans are addicted to illicit drugs, alcohol, tobacco and other substances including opioids, with both immediate and long-term harm to not just themselves, but also family, friends and society.
Unique DNA loops found outside regular chromosomes are linked to poor clinical outcomes in aggressive childhood brain cancers. The new study, led by Lukas Chavez and published in Nature Genetics, may transform the treatment of these rare cancers.
New research has demonstrated a way to accelerate recovery from peripheral nerve injury by targeting an enzyme that was thought to be responsible for muscle wasting with aging.
A study led by Institute scientists suggests an entirely new approach to treat pancreatic cancer. The research shows that feeding tumors a copycat of an important nutrient starves them of the fuel they need to survive and grow.
Zeroing in on hepatic myofibroblasts while simultaneously addressing the underlying cause(s) of liver damage may be the key to reversing liver fibrosis. A new review by David Brenner, M.D., describes the emerging therapeutic approach.