Opinion: Mistakes and misconduct in science are not synonymous; there are remedies for both - Sanford Burnham Prebys
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Opinion: Mistakes and misconduct in science are not synonymous; there are remedies for both

AuthorCommunications
Date

April 22, 2024

Skepticism is important to science, but critical thinking even more so. Many Americans don’t  believe in science. Scientists need to change minds.

From climate change to vaccines, science seems under attack everywhere on every topic, though often for reasons having little to do with actual research and evidence.

Science should always be questioned. That’s part of the process. But when people fundamentally and without consideration do not trust scientists, when they believe there are ulterior motives, we’re in trouble.

Feeding those suspicions are regular headlines reporting scientific fraud and misconduct. For as long as there has been science, there have been such cases, and we rightfully wring our hands when they come to light. But is this a time of crisis in science ethics? The answer, like science itself, is more complicated than blaring headlines.

In 2005, The New York Times described scientific fraud a “global trend.” A review of biomedical and life science research articles published between 1973 and 2012 noted more than 2,000 papers had been retracted, but less than one-quarter for technical errors. The majority were primarily pulled for fraud or suspected fraud, duplicate publication or plagiarism.

Scientific journals, universities and research institutions have long struggled to effectively combat fraud, with mixed results. Many of the revelations leading to retractions of published work are the result of independent sleuths or enterprises. PubPeer is a website self-described as an “online journal club” where mostly anonymous investigators cull published data for scientific errors or dubious conclusions, from too-small sample sizes and bias to doctored or misleading images.

Sometimes the detected offense is fraud, which should be dealt with accordingly. At other times, researchers are taken to task for unintentional errors or findings that were, when published, the best thinking.

Should scientists be responsible for all research they’ve conducted or published under their name? It sounds reasonable, but it’s counterproductive. I have published or authored more than 300 scientific papers, articles, reviews and chapters in books. Do I “own” those findings forever? Am I obliged to correct and update them whenever

Doing so might mean spending more time looking backward than forward. That’s not how science works. Like all researchers, my work is open to review, replication, correction and advancement (or dismissal) by others. New discoveries and technologies routinely upend older assumptions. That’s progress.

We should always be willing to correct mistakes in publications whenever they are detected, even if the papers and articles are many years old, and no longer represent current thinking.

To expect an older published manuscript to hold up to a state-of-the-art analysis sets an unfair standard. Researchers today have tools, technologies and knowledge that didn’t exist even a few years ago. Independent investigators need to exercise wisdom and context when considering the circumstances of older work—and still vigilantly maintain scientific integrity.

What are non-scientists supposed to make of these controversies and contretemps? It’s easy to simply ignore or dismiss them—and their relevance and benefits to society. Public trust in scientists and the belief that science has a positive effect on society has steadily declined in recent years, exacerbated by the politicized pandemic.

But that reflects a lack of critical thinking, which is, well, critical to our social well-being. More than ever, Americans need to be able to identify fact from fiction, to choose experts wisely and to draw valid conclusions from the same data, even when they do not conform to pre-existing biases.

Science isn’t about beliefs, intuition or gut feelings. It’s about empirical, verifiable facts. Sometimes those facts will later be proved incorrect with new data. That’s when minds must change along with the science.

Researchers make mistakes. Some even commit fraud. There are remedies which should be broadly and dispassionately pursued—and

Research institutions can do better in monitoring and correcting science. We should provide our scientists with the analytical resources needed to interrogate their manuscripts prior to submission to a peer-reviewed journal, such as online databases of citations, text mining and AI-driven technologies.

We should take all credible accusations of scientific error seriously and be willing to conduct independent investigations in response to concerns expressed by the scientific community.

It is a rare and hard-earned privilege to conduct research and we must hold ourselves to the highest standards. If non-scientists believe we are doing so, they can believe again in science.