Immunity, Inflammation and Microbiology
Helping Ourselves
The ability to fend off infectious diseases, which represent a mortal threat to millions, rests with the body’s immune system, which provides protection through various, layered and complex defenses.
If the immune system fails to function properly, if it becomes too weak, it can increase susceptibility to infectious disease. If it becomes too strong or dysfunctional, it can result in harmful inflammation and autoimmune diseases such as lupus and arthritis and even cancer.
By studying pathogen-host interactions, innate and humoral immunity, inflammation and T cell checkpoint regulation at even the smallest of interactions, we seek to better understand how the immune system works, why it sometimes doesn’t and find new treatments for endemic and pandemic infectious diseases, autoimmune disorders, cancer and inflammatory conditions.
News
Nov 20, 2024Decoding and debugging biological programs for a healthier future
Nov 20, 2024New Sanford Burnham Prebys scientist Alessandro Vasciaveo uses computational expertise to deepen understanding of diseases.
Nov 19, 2024Protein superfamily crucial to the immune system experiences Broadway-style revival
Nov 19, 2024San Diego scientists note a resurgence of interest in research on protein family to find new drug candidates.
Nov 18, 2024Science in Pictures
Nov 18, 2024A weekly image series featuring selected pictures in science • Madagascar giant day gecko hand
Nov 13, 2024Decades of dedication led to FDA approval of a new treatment for Duchenne Muscular Dystrophy
Nov 13, 2024Nearly 30 years of discoveries by a Sanford Burnham Prebys scientist and collaborators lead to federal approval of the first…
Nov 13, 2024Stem cell pioneer Su-Chun Zhang Joins Sanford Burnham Prebys
Nov 13, 2024Acclaimed stem cell scientist Su-Chun Zhang, MD, PhD, whose work has profoundly changed both understanding of how brain cells work…
Nov 11, 2024Seven questions for FDA advisor Evan Snyder
Nov 11, 2024Sanford Burnham Prebys physician-scientist advises the FDA on cell-based therapeutics, tissue engineering and gene therapies.