Science in Pictures - Sanford Burnham Prebys
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Science in Pictures

AuthorScott LaFee
Date

August 26, 2024

The distribution of metabolites (small molecules produced while chemical reactions take place in a cell to provide energy) in cells in a mouse kidney. Three small molecules (the amino acids aspartate and glutamine and the antioxidant glutathione) were visualized using a technique called computational molecular phenotyping (CMP). Grayscale light micrographs were taken of silvered antibodies against aspartate, glutamine and glutathione and these were then digitally converted into red, blue and green respectively.

Image courtesy of Jefferson R. Brown, Robert E. Marc, Bryan W. Jones, Glen Prusky and Nazia Alam.