Dr. Mahmoud received his PhD from UT Southwestern and completed his postdoctoral training at Harvard University. His laboratory investigates the molecular and cellular mechanisms governing cardiovascular development and regeneration. He has pioneered innovative approaches to studying mammalian heart regeneration, recently demonstrating that metabolic reprogramming can promote adult cardiomyocyte proliferation, revascularization, and regeneration following cardiac injury. Additionally, his lab explores how metabolism influences the transcriptional and epigenetic landscape of heart regeneration. Dr. Mahmoud’s research also seeks to define the mechanisms that regulate adult cardiomyocyte cell cycle re-entry and sarcomere disassembly using genetic and proteomic approaches.
Education and Training
2102-2017: Postdoctoral Fellow, Harvard University, Cambridge, MA
2007-2012: PhD, UT Southwestern Medical Center, Dallas, TX
2000-2005: BSc, Cairo University, Egypt
Honors and Recognition
2023: WARF Innovation Award
2023: Vilas Associate Award
2019: American Heart Association Career Development Award
2018: Wisconsin Partnership Program New Investigator Award
2015: American Heart Association Postdoctoral Fellowship Training Award
2014: Harvard Stem Cell Institute Mentorship Award
2011: UT Southwestern Award of Excellence
2010: American Heart Association Predoctoral Fellowship Training Award