Pamela Itkin-Ansari PhD
Adjunct ProfessorCenter for Cardiovascular and Muscular Diseases
EmailLab Website
Pamela Itkin-Ansari earned her PhD in Biomedical Sciences from the University of California, San Diego, in 1999. She received postdoctoral training focused on diabetes at that same organization. In 2003, Dr. Itkin-Ansari was appointed Assistant Professor in the Department of Pediatrics, UC San Diego. She moved her laboratory to Sanford Burnham Prebys in 2005.
California Institute for Regenerative Medicine (CIRM)
Falk Foundation
The Hartwell Foundation
The Hirshberg Foundation
Juvenile Diabetes Research Foundation (JDRF)
National Institutes of Health
2013-2014: Outstanding Faculty Mentor Award, UCSD
2011-2014: Hartwell Foundation Biomedical Research Award
2011: Invited Speaker, TEDx
2008-2013: Board of Directors, JDRF San Diego
2008: Health Hero Leadership Award, Combined Health Agencies of San Diego
2012-current: Islet Society
2010-current: ASGCT
2008-current: Board of Directors, JDRF San Diego chapter
2008-2013: JDRF board of directors, San Diego
2007-current: American Association for Cancer Research
2007-current: American Diabetes Association
2007-current: American Pediatric Society/Society for Pediatric Research
2006-current: AAAS
Related Disease
Cancer, Diabetes – General, Gastric Cancer, Monogenic Diabetes, Pancreatic Cancer, Type 1 Diabetes, Type 2 Diabetes
Dr. Itkin-Ansari’s research is directed toward understanding diseases of the human pancreas.
Areas of focus are: 1) developing a cell-based therapy for diabetes that does not require immunosuppression, and 2) identifying proteins required for proper insulin production and processing.
Islet clusters in the developing pancreas
The lab determined how dysregulation of specific transcription factors triggers pathogenic cell cycle entry in normal pancreatic cells. This master signaling pathway controlling pancreatic cancer cell growth is yielding potential targets for drug discovery.
Id3 (green) in human pancreatic cancer
Sanford Burnham Prebys scientists bring dramatic stories of scientific achievement to life.
The 2024 PancWest Symposium brought more than 120 scientists to the Sanford Burnham Prebys campus in San Diego to discuss…
Cancer Center open house connects San Diego community with scientists working toward cancer cures
Research led by Pamela-Itkin-Ansari, PhD, and Randal Kaufman PhD, has mapped out a network of biochemical interactions that help special…
Study reveals previously unknown protein that helps proinsulin fold and opens new avenues for diabetes research Scientists at Sanford Burnham…
Pamela Itkin-Ansari, PhD, adjunct assistant professor in the Development, Aging, and Regeneration Program at SBP, participated in the grand opening…
Tran DT, Pottekat A, Lee K, Raghunathan M, Loguercio S, Mir SA, Paton AW, Paton JC, Arvan P, Kaufman RJ, Itkin-Ansari P
J Clin Endocrinol Metab 2022 Nov 23 ;107(11):3100-3110Lee YJ, Nam EJ, Kim S, Kim YT, Itkin-Ansari P, Kim SW
Cancers (Basel) 2022 Jun 12 ;14(12):Liu M, Huang Y, Xu X, Li X, Alam M, Arunagiri A, Haataja L, Ding L, Wang S, Itkin-Ansari P, Kaufman RJ, Tsai B, Qi L, Arvan P
J Clin Invest 2021 Jan 19 ;131(2):Tran DT, Pottekat A, Mir SA, Loguercio S, Jang I, Campos AR, Scully KM, Lahmy R, Liu M, Arvan P, Balch WE, Kaufman RJ, Itkin-Ansari P
Diabetes 2020 Aug ;69(8):1723-1734Scully KM, Lahmy R, Signaevskaia L, Sasik R, Medal R, Kim H, French R, James B, Wu Y, Lowy AM, Itkin-Ansari P
Cell Mol Gastroenterol Hepatol 2018 ;6(2):181-198Kim S, Lahmy R, Riha C, Yang C, Jakubison BL, van Niekerk J, Staub C, Wu Y, Gates K, Dong DS, Konieczny SF, Itkin-Ansari P
Pancreas 2015 Jul ;44(5):718-27