Cell Death and Survival Networks Archives - Sanford Burnham Prebys
Institute News

How arsenic cures leukemia

Authorsgammon
Date

June 18, 2015

For the first time, Sanford-Burnham researchers have shown how the reversible interactions of the small protein SUMO work to facilitate treatment of acute promyelocytic leukemia (APL). The study, published recently in the journal Science Signaling, explains how the on-off associations of SUMO are required to destroy the APL causing oncoprotein and pave the way for an arsenic-based cure. Continue reading “How arsenic cures leukemia”

Institute News

How tumors remodel their surroundings to grow

Authorsgammon
Date

July 7, 2014

A team of scientists from Sanford Burnham Medical Research Institute (Sanford-Burnham) has found that the loss of a protein called p62 in the cells and tissue surrounding a tumor can enhance the growth and progression of tumors. The study suggests that therapies targeting the tumor microenvirnoment may be as important as targeting the tumor itself. Continue reading “How tumors remodel their surroundings to grow”