Conrad Prebys Center for Chemical Genomics Archives - Page 2 of 2 - Sanford Burnham Prebys

Tag: Conrad Prebys Center for Chemical Genomics

Institute News

SBP Collaborates with NIH’s Translational Science Center on pancreatic cancer

Authorsgammon
Date

October 13, 2015

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The National Center for Advancing Translational Sciences (NCATS) has initiated a novel collaborative study with Pamela Itkin-Ansari, PhD., to screen for drugs that reprogram pancreatic cancer cells back to a normal, non-threatening phenotype. The collaboration is based on Itkin-Ansari’s research and development of a screening platform to find drugs that induce the overexpression of E47, a protein that binds to specific DNA sequences, causing cells to differentiate to acinar cells—cells with normal pancreatic cell traits and characteristics.

Continue reading “SBP Collaborates with NIH’s Translational Science Center on pancreatic cancer”

Institute News

Pathway that controls cancer cell proliferation discovered

Authorsgammon
Date

August 13, 2015

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In a new study by SBP, researchers have identified a novel kinase cascade that regulates mTORC1, a protein complex implicated in the control of cancer cell growth in response to nutrients. The study, published in Cell Reports, provides further insight into the control of mTORC1 activation, and highlights several new potential drug targets to treat human pathologies linked to mTORC1 deregulation. Continue reading “Pathway that controls cancer cell proliferation discovered”

Institute News

SBP spin-out company micro-gRx receives $200,000 Space Florida award

Authorpbartosch
Date

July 20, 2015

siobhan malany

We’re excited to announce that the first funded company established based on work emerging from our Lake Nona campus, micro-gRx Incorporated, has received a $200,000 award from Space Florida through the Florida – Israel Innovation Partnership Program. micro-gRx is partnering with R&D company SpacePharma to develop a “lab on a chip” research model that enables scientists to study live human cells in microgravity. Continue reading “SBP spin-out company micro-gRx receives $200,000 Space Florida award”

Institute News

New collaboration strives to find novel treatment approaches for cardiovascular disease

Authorpbartosch
Date

May 28, 2015

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Sanford-Burnham today announced it has signed a two-year partnership agreement with Takeda Pharmaceutical Company Ltd. of Japan to study the potential role of several gene regulatory proteins as targets for the treatment of heart failure. Based on research conducted in Sanford-Burnham laboratories, the collaborating scientists will screen and develop molecules that have the potential to improve the metabolism and function of the failing heart. Continue reading “New collaboration strives to find novel treatment approaches for cardiovascular disease”

Institute News

LEAD San Diego visits Sanford-Burnham in La Jolla

Authorrbruni
Date

May 13, 2015

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On Tuesday, May 5, Sanford-Burnham hosted LEAD San Diego, a local civic leadership organization that helps emerging and seasoned leaders in all sectors of the San Diego community expand their skills and enhance their knowledge of the local business enterprises, for a special breakfast and tour.

The visitors enjoyed a welcome by Institute CEO Dr. Perry Nisen before embarking on a tour of the state-of-the-art La Jolla, Calif., facilities.

Tour highlights included a stop at the Conrad Prebys Center for Chemical Genomics, where Dr. Anne Bang, Director, Cell Biology, gave a brief overview on  how the Institute utilizes cutting-edge technology to identify the precise small molecules that will become the building blocks of future medicines.

The visitors also had the opportunity to stop by the Center for Stem Cell Biology and Regeneration, where Dr. Yang Liu, a visiting researcher in the lab of Dr. Evan Synder, Professor, Human Genetics Program, gave them an overview of the Institute’s stem cell studies.

If you would like to arrange a visit to the Institute, please email Sandy Hanna at shanna@sanfordburnham.org or call (858)795-5056.

Dr. Yang Liu shares information on the Stem Cell Core with LEAD San Diego tour members.

Dr. Anne Bang with the LEAD San Diego group.LEAD San Diego Tour

Institute News

Sanford-Burnham small molecule licensed to Daiichi Sankyo

Authorpbartosch
Date

April 21, 2015

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We’re excited to announce that Sanford-Burnham has signed a licensing agreement with Daiichi Sankyo to further develop a first-in-class small molecule for the treatment of cardiovascular-metabolic disease. The small molecule is based on longstanding, groundbreaking biology work by one of our scientists and his laboratory team, who for decades focused their research on treating a consequence of cardiovascular-metabolic disease. Continue reading “Sanford-Burnham small molecule licensed to Daiichi Sankyo”

Institute News

Sanford-Burnham plays key role in San Diego Alzheimer’s Project

Authorsgammon
Date

December 10, 2014

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San Diego has formed an unprecedented coalition to find a cure for Alzheimer’s disease. The Alzheimer’s Project, conceived of by county Board of Supervisors Chairwoman Dianne Jacob, is an initiative with aims of both finding a cure and helping the 60,000 county residents who have the disease. Guided by a steering committee led by Jacob and chaired by Supervisor Dave Roberts, the Project brings a diverse team of experts in research, caregiving, health care, philanthropy, and community support to assimilate and execute a five-year plan with a goal to conquer the disease once and for all. Continue reading “Sanford-Burnham plays key role in San Diego Alzheimer’s Project”

Institute News

Sanford-Burnham wins GlaxoSmithKline drug discovery challenge

Authorpbartosch
Date

December 1, 2014

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We’re excited to announce that a joint team of scientists from Sanford-Burnham at Lake Nona and Mayo Clinic has been selected as a winner of GlaxoSmithKline (GSK)’s 2014 Discovery Fast Track Challenge. The Challenge is designed to accelerate the translation of academic research into novel therapies. Researchers from the two organizations will work with partners at GSK to screen the pharmaceutical company’s library of compounds for potential new drugs to treat resistant hypertension, blood pressure that remains high despite treatment with current medications. The Challenge provides resources for small-molecule discovery and offers the opportunity for long-term collaboration. Continue reading “Sanford-Burnham wins GlaxoSmithKline drug discovery challenge”

Institute News

Sanford-Burnham commends summer 2014 high-school researchers

Authorrbruni
Date

July 24, 2014

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On July 18, eleven students from The Preuss School UCSD celebrated the completion of an intensive two-week summer research program with a poster symposium and luncheon at our La Jolla, Calif., campus. The Preuss School is a unique, charter middle and high school for low-income, highly motivated students who strive to become the first in their families to graduate from college. Continue reading “Sanford-Burnham commends summer 2014 high-school researchers”