Journal of Cell Biology Archives - Sanford Burnham Prebys
Institute News

Cells on the run: researchers discover a protein required for cell motility

Authorsgammon
Date

April 28, 2015

Your cells move. They need to move for good reasons, such as when white blood cells travel to heal wounds, and for bad reasons, like when cancer cells invade surrounding tissue to metastasize. To move, cells create extensions—like feet—that make contact with a surface and lead the cell to its destination. The abnormal production of these cell extensions is associated with Alzheimer’s disease, epilepsy, and many other neurological disorders. For these reasons, scientists are working to understand the fundamental components of cell movement. What they find may lead to treatments that can promote cell movement when you need it, and prevent it when you don’t. Continue reading “Cells on the run: researchers discover a protein required for cell motility”

Institute News

New insights into how the heart forms may help identify heart defects

AuthorGuest Blogger
Date

September 29, 2014

This is a post by our guest writer Janelle Weaver, PhD

The formation of the heart during development is a highly complex process that requires precise coordination between cells and molecular signaling pathways. The fruit fly has been widely used for studying the underlying cellular and molecular mechanisms, and a great deal is known about how the fate of heart cells is controlled by signaling pathways and transcription factors—proteins that control gene activity. But beyond that, events that regulate heart formation have not been clear. Continue reading “New insights into how the heart forms may help identify heart defects”