mTOR Archives - Sanford Burnham Prebys
Institute News

Pathway that controls cancer cell proliferation discovered

Authorsgammon
Date

August 13, 2015

In a new study by SBP, researchers have identified a novel kinase cascade that regulates mTORC1, a protein complex implicated in the control of cancer cell growth in response to nutrients. The study, published in Cell Reports, provides further insight into the control of mTORC1 activation, and highlights several new potential drug targets to treat human pathologies linked to mTORC1 deregulation. Continue reading “Pathway that controls cancer cell proliferation discovered”

Institute News

How tumors remodel their surroundings to grow

Authorsgammon
Date

July 7, 2014

A team of scientists from Sanford Burnham Medical Research Institute (Sanford-Burnham) has found that the loss of a protein called p62 in the cells and tissue surrounding a tumor can enhance the growth and progression of tumors. The study suggests that therapies targeting the tumor microenvirnoment may be as important as targeting the tumor itself. Continue reading “How tumors remodel their surroundings to grow”