Siobhan Malany, PhD, director of Translational Biology at Sanford Burnham Prebys Medical Discovery Institute at Lake Nona (SBP) and founder of the Institute’s first spin-off company, Micro-gRx, Inc., has been awarded $435,000 to study atrophy in muscle cells in microgravity on the International Space Station (ISS). In microgravity, conditions accelerate changes in cell growth similar to what occurs in the aging and disease process of tissues. Using real-time analysis, Malany will be able to rapidly study cells for potential new therapeutic approaches to muscle degeneration associated with aging, injury or illness. Continue reading “Siobhan Malany, PhD, selected to conduct novel medical research in space”
Tag: Siobhan Malany
SBP scientists join race for a cure
Andrew Carley, PhD, has a personal motivation for finding a cure for diabetes. As one of the 29 million Americans with diabetes, he became a biomedical researcher to better understand the causes of disease.
For Julio Ayala, PhD, a passion for medical research was sparked by his grandmother, a type 1 diabetic, who at age 86 has successfully managed the disease most of her life.
Siobhan Malany, PhD, is an avid cyclist who believes so strongly in team efforts that she has enlisted robots to join her research team searching for new drugs to fight disease.
On Sunday, March 13, 2016, these Sanford Burnham Prebys scientists took their interest in biomedical research to the roadways of Central Florida as they joined 1,100 participants in the 2016 Tour de Cure at Lake Nona bicycle ride for diabetes. The twelve-member SBP team collectively pedaled more than 400 miles and raised $9,000 to fight the disease. Participants began the 25, 63, and 100-mile courses in Lake Nona Medical City near SBP and the Center for Metabolic Origins of Disease, the site where researchers study diabetes in hopes of identifying new, more effective therapies.
“It was a fun way to give back and do what I love to do. Cycling has been my commute, my sport and my escape —now it’s a way to contribute,” said Malany, who completed the 100-mile course in five hours. She enjoyed the camaraderie and credited the group with a bit of competitive motivation. “I kept a 21.5 mile per hour pace, which was not something I would have accomplished had I been cycling alone. It was fast and fun being in a pack because you conserve energy by drafting,” added Malany.
Since moving to Lake Nona in December from Chicago, Carley has gotten back into cycling and now bikes to the Institute in Medical City each day. He completed a Century ride to mark the 20th anniversary of the Tour de Cure in 2011 in Chicago and decided to mark the 25th anniversary of the event with a 25 mile ride. “I selected the 25 mile course because it was the maximum length of time my 3-year old daughter would remain content in her bike stroller watching a Toy Story movie. She weighs only 32 pounds and the course was relatively flat so we were able to complete the ride in two hours despite frequent stops,” said Carley.
Team captain Ayala participated in various ADA and JDRF fund raising events while at Vanderbilt University. “While riding my bike to work a few years ago, I saw the first Tour de Cure in Lake Nona and knew that I wanted to participate. We study diseases of metabolism at the Medical City site and a number of faculty, including me, receive ADA-funded grants, so I wanted to get involved,” said Ayala.
Ayala credits the team’s spirit with providing extra motivation to push through the extreme winds encountered on the course. It’s with similar determination that they approach their daily race for the cure in their research labs.
SBP spin-out company micro-gRx receives $200,000 Space Florida award
We’re excited to announce that the first funded company established based on work emerging from our Lake Nona campus, micro-gRx Incorporated, has received a $200,000 award from Space Florida through the Florida – Israel Innovation Partnership Program. micro-gRx is partnering with R&D company SpacePharma to develop a “lab on a chip” research model that enables scientists to study live human cells in microgravity. Continue reading “SBP spin-out company micro-gRx receives $200,000 Space Florida award”
Happy Holidays from Sanford-Burnham!
As the year draws to a close, we look back on Sanford-Burnham’s many achievements in 2014. Over the year, our scientists published numerous papers in high-profile journals; secured significant grant funding; partnered with companies, institutes, and nonprofit organizations from across the country and the globe; and they took important steps toward our ultimate goal – to have a tangible impact on human health. Here are 14 accomplishments of 2014 that we are proud to share with you: Continue reading “Happy Holidays from Sanford-Burnham!”
Sanford-Burnham wins GlaxoSmithKline drug discovery challenge
We’re excited to announce that a joint team of scientists from Sanford-Burnham at Lake Nona and Mayo Clinic has been selected as a winner of GlaxoSmithKline (GSK)’s 2014 Discovery Fast Track Challenge. The Challenge is designed to accelerate the translation of academic research into novel therapies. Researchers from the two organizations will work with partners at GSK to screen the pharmaceutical company’s library of compounds for potential new drugs to treat resistant hypertension, blood pressure that remains high despite treatment with current medications. The Challenge provides resources for small-molecule discovery and offers the opportunity for long-term collaboration. Continue reading “Sanford-Burnham wins GlaxoSmithKline drug discovery challenge”