Alexandre Colas PhD
Associate Dean of AdmissionsGraduate School of Biomedical Sciences
Associate ProfessorCenter for Cardiovascular and Muscular Diseases

Dr. Colas earned his PhD from the Universite Pierre et Marie Curie, Paris, France.
2011-2013: American Heart Association Post-Doctoral Fellowship
2011: Best Talk Award (Development & Aging Post-Doctoral Retreat, Sanford Burnham Prebys)
2010-2011: California Institute for Regenerative Medicine Post-Doctoral Fellowship
2006-2007: French Myopathy Association PhD Fellowship
2003-2006: Ministry of French Research PhD Fellowship
2000-2001: Erasmus Undergraduate Fellowship
Related Disease
Cardiomyopathies, Cardiovascular Diseases, Heart Disease
Phenomena or Processes
Cardiovascular Biology, Cell Biology, Development and Differentiation, Embryogenesis, Embryonic/Pluripotent Stem Cells, Regenerative Biology, RNA-Based Gene Regulation, Transcription Factors
Our laboratory focuses on the identification and reconstruction of novel regulatory pathways controlling the determination and the acquisition of cardiovascular cell fates in humans. To that end, our team has developed a unique set of cell-based assays suitable for high-throughput functional screening, which enables the implementation of unbiased and systematic experimental approaches with unprecedented exploratory power. Our goal is to leverage generated knowledge to produce better cardiomyocytes to model cardiac diseases in-a-dish as well as to devise innovative cardiac regenerative strategies. In parallel, our lab is also dedicated to identify and develop new drugs promoting cardiac regeneration and/or helping preserving heart function after injury.
Colas was applauded for enthusiastically promoting mentees’ professional and scientific development.
A collaborative study led by Institute researchers is paving the way to identifying gene networks that cause atrial fibrillation (AFib),…
Cunningham TJ, Brade T, Sandell LL, Lewandoski M, Trainor PA, Colas A, Mercola M, Duester G
PLoS One 2015 ;10(9):e0137894Mercola M, Colas A, Willems E
Circ Res 2013 Feb 1 ;112(3):534-48McKeithan WL, Colas AR, Bushway PJ, Ray S, Mercola M
Curr Protoc Stem Cell Biol 2012 Nov ;Chapter 1():Unit 1F.13