Phenotypic Screening Archives - Sanford Burnham Prebys

Dr. Susanne Heynen-Genel has over 20 years of experience in image-based screening systems, including automated microscopy instrumentation, image analysis, algorithm development, and HCS assay design. She has been directing development and execution of image-based high-content assays for high-throughput screening (primary screens of large chemical and RNAi libraries) and small scale screening (secondary assays, focused libraries assays for validation of basic research findings) for ten years at the Conrad Prebys Center for Chemical Genomics. 

Prior to joining Sanford Burnham Prebys, Susanne was a staff systems scientist at Beckman Coulter, where her responsibilities included system design and integration of high-content screening systems and applications. Previous to that she was an applications scientist for high-throughput microscopy systems at Q3DM until its acquisition by Beckman Coulter. She spent a year as postdoctoral researcher at the University of California in San Diego where she also received her PhD in Bioengineering in 2002. Her graduate student research focused on optimizing fluorometric performance of high-throughput microscopy systems to yield more accurate quantification. This work was incorporated in an image-based HCS platform commercialized first by Q3DM Inc. and then by Beckman Coulter. The accompanying image and single cell data analysis and classification work, initially aimed at detection of cancer cells for cytodiagnostics and presented at conferences, was on the forefront of high-throughput imaging analysis at the time and similar analyses algorithms have more recently been incorporated in commercial HCS image analysis software packages.

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