Interim Director Archives - Sanford Burnham Prebys

Dr. Commisso’s doctoral studies were focused on various aspects of endocytosis pertaining to Notch signal transduction. Specifically, he analyzed the role of an endocytic protein known as Neuralized, which functions in the internalization of Notch ligands such as Delta and Jagged. As a doctoral trainee he gained extensive experience in cell biological and biochemical techniques pertaining to cellular trafficking. Subsequently, Dr. Commisso received postdoctoral training in pancreatic cancer at New York University School of Medicine. In that capacity he gained expertise in analyzing the complex signaling events mediated by oncogenic Ras during the initiation and progression of the disease. Additionally, he has expertise in the utilization of mouse models of pancreatic cancer including heterotopic/orthotopic xenografts, syngeneic heterotopic/orthotopic implantation and autochthonous models.

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