Andrei Osterman Archives - Page 2 of 2 - Sanford Burnham Prebys
Institute News

New method to identify bacteria in the gut may facilitate development of probiotics

Authorjmoore
Date

January 19, 2016

The gut microbiome, the community of bacteria living in the intestines, has an enormous impact on human health, affecting risk for obesity, inflammatory bowel disease (IBD), neurological disorders, and even cancer. Accordingly, there has been an explosion of research in this area in the past ten years, with the long-term goal of developing ways to manipulate the microbiome to promote the survival of bacteria that promote health and/or eliminate those associated with disease. Continue reading “New method to identify bacteria in the gut may facilitate development of probiotics”

Institute News

Melanoma’s addiction to glutamine is the basis for cancer growth

Authorsgammon
Date

February 17, 2015

Researchers at Sanford-Burnham have discovered that without a source of glutamine—one of the 20 amino acids used to build proteins—melanoma cells will stop proliferating and die. Their craving for glutamine stems from their ability to “abuse” this essential nutrient by using it as an additional source of carbon and energy. The findings present a rational basis for a treatment strategy that limits the supply of glutamine to tumors, potentially through nutritional interventions or inhibitors of glutamine uptake. The results of the study appear online in Oncotarget today. Continue reading “Melanoma’s addiction to glutamine is the basis for cancer growth”