Annual Symposium Archives - Sanford Burnham Prebys
Institute News

Top neuroscientists gather at Sanford Burnham Prebys’ annual symposium

AuthorMonica May
Date

November 18, 2019

A mother who no longer remembers her son. A daughter who took doctor-prescribed pain medication and slipped into addiction. A father who has trouble grasping a pen and eventually becomes unable to walk. Neurological disorders are some of the most painful and complex conditions our society faces today. Yet much about the brain remains unknown, hindering our ability to help people with these disorders.

To help shed light on the brain’s mysteries, on November 1, 2019, more than 250 neuroscientists gathered at Sanford Burnham Prebys’ one-day symposium to share their latest discoveries. Organized by professors Jerold Chun, MD, PhD; Randal Kaufman, PhD; Barbara Ranscht, PhD; and Huaxi Xu, PhD, the event attracted scientists from around the world eager to learn more about biological clues that are leading to effective therapies. Read the full list of the invited speakers and their talks.

“Nearly every day we read about the toll neurological diseases such as Alzheimer’s, dementia, mental health disorders and more take on our society,” said Kristiina Vuori, MD, PhD, president of Sanford Burnham Prebys, in her introductory address. “Our symposium brings together scientists at the frontiers of brain research who share their latest discoveries to open new paths toward new and better treatments.”

More than 50 million Americans are affected by neurological disorders, including Alzheimer’s disease, dementia, addiction and more, according to the National Institute of Neurological Disorders and Stroke. Most of these conditions are not well addressed by current medicines.

At the symposium, world-renowned scientists from Stanford University, Mount Sinai, University of Vienna and other top-tier institutes gave talks describing their strategies to uncover the molecular basis of brain disorders and how these discoveries are advancing potential therapies. A national plan to address Alzheimer’s and other dementia types was described by Eliezer Masliah, MD, the National Institute of Aging’s director of the Division of Neuroscience.

“This was my first scientific conference, and it was perfect for learning about a wide range of cutting-edge brain research,” said attendee Jaclyn Beck, a PhD student at UC Irvine who studies the role of the brain’s immune cells, called microglia, in Alzheimer’s disease. “I have several pages of notes from the talks detailing findings I want to investigate and people I want to contact.”

For the past 40 years, our Institute has invited leading experts on one scientific topic to share their latest research at an annual symposium. By encouraging connection and collaboration, we hope to inspire insights that improve human health. The 41st annual symposium will take place in November 2020 and focus on the biology of organelles, specialized pouches within cells that carry out critical functions such as generating power and breaking down waste, and its role in health and disease.

Institute News

World-renowned scientists speak at SBP’s symposium on a booming research area: epigenetics

AuthorMonica May
Date

November 28, 2018

DNA contains more information than scientists previously thought. A booming field of research called epigenetics is uncovering DNA alterations that affect whether genes are turned on or off—without changing a single base pair. 

These epigenetic changes may be physical, such as winding or unwinding DNA to change its accessibility—akin to opening or closing a door. Other changes can be chemical, such as adding molecular tags that turn genes on or off—like a highlighter calling out special text to a reader. 

On October 29, 2018, more than 300 scientists gathered at SBP’s 39th Annual Symposium to hear the latest connections between epigenetics and development, aging, and diseases such as cancer. Researchers are particularly interested in this field because modifying epigenetic changes could be easier than editing the body’s underlying genetic code—and advances are leading to new medicines. 

Organized by SBP professors Peter Adams, PhD; Ani Deshpande, PhD; and Lorenzo Puri, MD, PhD, the event’s speakers hailed from Harvard Medical School, Massachusetts Institute of Technology, Stanford University and other world-renowned institutions. 

Tweet by scientists praising the symposium
  USC assistant professor Bérénice A. Benayoun, PhD,
  praised the symposium on Twitter

After a welcome by SBP’s President Kristiina Vuori, MD, PhD, talks commenced on topics ranging from the role of epigenetics in prostate cancer, development of the heart and aging. Unpublished work was frequently presented, meaning that attendees received the most up-to-date results available. 

A full list of speakers is listed below. To read more insights, follow #SBPsymposium on Twitter. And be sure to look out for next year’s symposium, which will focus on neurodegenerative diseases.

  • Anne Brunet, Stanford University – Epigenetic and metabolic regulation of aging 
  • Chris Glass, University of California, San Diego – Nature and nurture of tissue resident macrophages 
  • Cigall Kadoch, Dana-Farber Cancer Institute and Harvard Medical School – Structure and function of mammalian SWI/SNF complexes in human cancer 
  • Manolis Kellis, Massachusetts Institute of Technology – From genomics to therapeutics: dissection and manipulation of human disease circuitry at single-cell resolution 
  • Peter Lewis, Wisconsin Institute for Discovery – Mechanistic dissection of oncogenic histone mutations 
  • Barbara Meyer, University of California, Berkeley – Dynamic control of X-chromosome topology and gene expression during development via chromatin modification and condensing 
  • Raul Mostoslavsky, Harvard Medical School – Linking epigenetics, metabolism and cancer: new clues from SIRT6
  • Bing Ren, University of California, San Diego – Remodeling of chromatin organization during human cardiomyocyte differentiation 
  • Peggy Farnham, University of Southern California – CRISPR-mediated deletion of prostate cancer risk elements identifies repressive chromatin loops 
Institute News

SBP’s 37th Annual Symposium: Aging and Regeneration

Authorsgammon
Date

November 3, 2015

On Friday, October 30, more 350 people came to SBP’s 37th Annual Symposium to hear leading scientists present their latest research on aging and regeneration.  The presenters, listed here, provided valuable insight into the latest studies on what causes aging, and strategies to repair injuries, prolong life, and prevent diseases.  The event was hosted by (from left to right): Rolf Bodmer, PhD, Malene Hansen, PhD, (in bee costume for Halloween) Alexey Terskikh, PhD

 

organizers-symposium-beaker

Many congratulations to Esther Minotti for successfully organizing the event!

symposium-photo-beaker

And many thanks to the Glenn Foundation for Medical Research for their support.

Institute News

Happy Holidays from Sanford-Burnham!

Authorpbartosch
Date

December 23, 2014

As the year draws to a close, we look back on Sanford-Burnham’s many achievements in 2014. Over the year, our scientists published numerous papers in high-profile journals; secured significant grant funding; partnered with companies, institutes, and nonprofit organizations from across the country and the globe; and they took important steps toward our ultimate goal – to have a tangible impact on human health. Here are 14 accomplishments of 2014 that we are proud to share with you: Continue reading “Happy Holidays from Sanford-Burnham!”

Institute News

Sanford-Burnham’s 36th Annual Symposium: The Microbiome and Human Health

Authorsgammon
Date

November 3, 2014

On Thursday, October 30, 2014, Sanford-Burnham hosted more than 250 attendees at its 36th annual symposium to hear opinion-leading scientists discuss their latest findings on the microbiome. The microbiome is a relatively new frontier for research scientists with aims to understand how the trillions of microbes—bacteria, viruses, fungi, and others—that live in our nose, mouth, gut, and skin interact with human cells to influence health and disease. Continue reading “Sanford-Burnham’s 36th Annual Symposium: The Microbiome and Human Health”