body mass index Archives - Sanford Burnham Prebys
Institute News

New links between heart hormones, obesity, and diabetes

AuthorGuest Blogger
Date

February 17, 2016

New research from SBP’s Sheila Collins, PhD, and Richard Pratley, MD, has revealed an important relationship between proteins secreted by the heart and obesity, glucose intolerance, and insulin resistance. The findings, published in Obesity, offer a new approach to treating metabolic disorders, including type 2 diabetes, by targeting the pathway that controls the proteins’ concentration in the blood. Continue reading “New links between heart hormones, obesity, and diabetes”

Institute News

Exercise following bariatric surgery provides health benefits

Authorsgammon
Date

December 1, 2014

A new study by researchers at the Florida Hospital – Sanford-Burnham Translational Research Institute for Metabolism and Diabetes (TRI-MD) in Orlando, Fla., shows that patients who moderately exercise after bariatric surgery (weight-loss surgery) gain additional health improvements in glucose metabolism and cardiorespiratory fitness compared to patients who lead a sedentary lifestyle after surgery. The findings confirm the physiological and potential clinical benefits of adding an exercise regime following weight-loss surgery. Continue reading “Exercise following bariatric surgery provides health benefits”

Institute News

Sanford-Burnham’s Steven R. Smith leads clinical study on new weight-loss treatment

Authorsgammon
Date

November 3, 2014

In a new pilot study led by principal investigator Steven R. Smith, MD, the weight-loss drug lorcaserin (LOR), was tested in combination with the drug phentermine (phen) to compare safety and weight loss to administration of LOR alone. The results showed that the combination of drugs more than doubled weight loss achieved compared to LOR alone, and that treatment with LOR plus phen was not associated with any additional adverse events compared either drug alone. Continue reading “Sanford-Burnham’s Steven R. Smith leads clinical study on new weight-loss treatment”

Institute News

A new link between obesity, inflammation, and insulin resistance

Authorsgammon
Date

July 17, 2014

A new study by researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) has identified a new signal that triggers the events leading to insulin resistance in obesity. The signal causes inflammation in adipose tissue and leads to metabolic disease. The study, published July 17 in Cell Metabolism, suggests that blocking this signal may protect against the development of metabolic disease, type 2 diabetes, and other disorders caused by obesity-linked inflammation. Continue reading “A new link between obesity, inflammation, and insulin resistance”