cancer therapy Archives - Page 3 of 3 - Sanford Burnham Prebys
Institute News

Molecule that fixes “leaky” blood vessels can impact cancer, stroke, and blindness

Authorsgammon
Date

March 13, 2015

In a new study by Masanobu Komatsu, Ph.D., associate professor in the Cardiovascular Pathobiology Program and Tumor Microenvironment and Metastasis Programs, a cellular protein called R-Ras was found to suppress the effects of vascular endothelial growth factor (VEGF), a signaling molecule that helps create new blood vessels and is overexpressed in many tumors. The findings create a new route to treat cancer as well as certain causes of blindness and ischemic diseases. Continue reading “Molecule that fixes “leaky” blood vessels can impact cancer, stroke, and blindness”

Institute News

Study explains control of cell metabolism in patient response to breast cancer drugs

Authorsgammon
Date

March 9, 2015

A new research study has discovered a mechanism that explains why some breast cancer tumors respond to specific chemotherapies and others do not. The findings highlight the level of glutamine, an essential nutrient for cancer development, as a determinant of breast cancer response to select anticancer therapies, and identify a marker associated with glutamine uptake, for potential prognosis and stratification of breast cancer therapy. The study results were published online in Cancer Cell. Continue reading “Study explains control of cell metabolism in patient response to breast cancer drugs”