Elena Pasquale Archives - Sanford Burnham Prebys

Tag: Elena Pasquale

Institute News

The Collaboration 4 Cure Alzheimer’s research awards announced at SBP

Authorsgammon
Date

October 29, 2015

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On October 28, Mayor Kevin Faulconer, County Supervisor Diane Jacob, San Diego philanthropist Darlene Shiley, and Mary Ball, president and CEO of the Alzheimer’s Association San Diego, came to SBP to announce the recipients of research awards from San Diego’s Dementia Drug Discovery Collaborative Program, “Collaboration 4 Cure (C4C).” The awards are part of an innovative program to harvest the best research ideas toward effective treatment of Alzheimer’s disease. Continue reading “The Collaboration 4 Cure Alzheimer’s research awards announced at SBP”

Institute News

Using geometry to design new drugs

Authorsgammon
Date

November 19, 2014

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In a new study published in ACS Chemical Biology, Sanford-Burnham’s Stefan Riedl and Elena Pasquale created a molecule with an improved ability to block the activation of a cell receptor called EphA4. When EphA4 is activated, it can hinder the ability of neurons to repair themselves and exacerbates certain degenerative processes, such as amyotrophic lateral sclerosis (ALS)—often referred to as Lou Gehrig’s Disease; Alzheimer’s disease; and stroke. The molecule is a cyclic peptide that represents a promising therapeutic lead for targeting neurodegenerative diseases and some cancers. Continue reading “Using geometry to design new drugs”