Uncategorized Archives - Sanford Burnham Prebys
Institute News

La Jolla research meeting convenes scientists studying aging

AuthorCommunications
Date

March 25, 2026

Scientists gathered at the 9th annual La Jolla Aging Meeting on Thursday, March 19, 2026, in the Salk Institute’s Conrad T. Prebys Auditorium

The event brought together 286 attendees and featured short talks from San Diego-based postdoctoral researchers and students studying the biology of aging.

Anamika Yadav, a research assistant in the lab of Sanju Sinha, PhD, at Sanford Burnham Prebys Medical Discovery Institute, discussed her work studying aging by detecting structural alterations in cells and tissues over time captured in images taken of routine medical biopsies. She used data from the Genotype-Tissue Expression Project, a major National Institutes of Health Common Fund initiative that gathered samples from 970 non-diseased individuals aged 20 to 70. Yadav trained a computational model on more than 25,000 histopathology slides from 40 tissue types to define aging patterns in different tissues. By this approach, Yadav defined distinct patterns of aging in different tissues which ultimately can help to predict specific diseases of aging.

Beatrice Silvestri, PhD, a postdoctoral associate in the lab of Yu Xin (Will) Wang, PhD, at Sanford Burnham Prebys, shared findings from her work on an enzyme called 15-hydroxyprostaglandin dehydrogenase (15-PGDH). Researchers have defined 15-PGDH as a gerontological enzyme or “gerozyme” due its connection with aging in multiple tissues. Silvestri presented results from studying the effects of blocking 15-PGDH to ameliorate the degeneration of the connection between motor neurons and skeletal muscle fibers. Inhibition of this gerozyme might have potential for healthy aging and prevention of many diseases of aging.

In addition to these podium presentations, four Sanford Burnham Prebys scientists shared their research results during the meeting’s poster sessions:

The 2026 La Jolla Aging Meeting concluded with a keynote address by Ana Maria Cuervo, MD, PhD, Distinguished Professor and Robert and Renée Belfer Chair for the Study of Neurodegenerative Diseases at Albert Einstein College of Medicine.

Peter Adams, PhD, director of the Cancer Genome and Epigenetics Program at Sanford Burnham Prebys, co-organized the La Jolla Aging Meeting with Alessandra Sacco, PhD, dean of the Sanford Burnham Prebys Graduate School of Biomedical Sciences and a professor in the Center for Cardiovascular and Muscular Diseases, and Salk Institute faculty members Jan Karlseder, PhD, and Gerald Shadel, PhD.

Institute News

Shanshan Yin named 2025 recipient of Eric Dudl Endowed Scholarship

AuthorGreg Calhoun
Date

March 24, 2026

Yin, a postdoctoral associate at Sanford Burnham Prebys, received the honor in recognition of her achievements in research on cancer and aging

Shanshan Yin, PhD, was named the 2025 recipient of The Eric Dudl Endowed Scholarship at Sanford Burnham Prebys Medical Discovery Institute. 

The scholarship fund was established at the institute to remember Eric Dudl, a postdoctoral researcher whose life was tragically cut short by cancer at the age of 33. Since 2007, 18 postdoctoral scientists have received support for their research from the endowed scholarship fund. 

Yin is a postdoctoral associate in the lab of Peter Adams, PhD, director of the Cancer Genome and Epigenetics Program at Sanford Burnham Prebys. She wants to understand why the incidence of cancer increases with age. Yin studies changes in gene expression and immune system activity in breast cancer tumors as mice age.  

Her research has shown that part of the reason that breast cancer is more common with age is because of an impaired immune system. Immune dysfunction due to aging allows the tumors to grow more frequently and more rapidly. Additional research on these findings may guide future preventive treatments.

Yin has garnered recognition throughout her scientific career, including the 2022 Lenka Finci and Erna Viterbi Fishman Fund Award from Sanford Burnham Prebys.  

“I’m grateful for the Dudl family’s kindness and generosity,” said Yin. “I am moved by Eric’s determination, bravery and love for life and for science, and I would like to carry his example with me going forward and do my best to honor his legacy.” 

“It’s been a real pleasure working with Shanshan over the years,” said Adams. “She truly does embody Eric Dudl’s commitment to and passion for science which is expressed so well by this inspirational award.”  

Eric Dudl

The Eric Dudl Endowed Scholarship at Sanford Burnham Prebys was established at the institute to remember Eric, a postdoctoral researcher whose life was tragicallycut shortby cancerat the age of 33.

For more information on setting up a scholarship or to learn more about our philanthropy program, please contact giving@sbpdiscovery.org. 

Institute News

Science in Pictures

AuthorCommunications
Date

March 23, 2026

Colorized scanning electron micrograph of surface of human skin. The outermost layer of skin is called the stratum corneum and is composed primarily of keratinocytes, living and dead. Dead cells form horny scales, and release peptides called defensins, which are part of the first line of immune defense mechanisms.

Image courtesy of Eye of Science/SPL.

Institute News

Science in Pictures

AuthorCommunications
Date

March 16, 2026

Colorized scanning electron micrograph depicts normal red blood cells (red, concave) with elongated blood cells indicative of sickle-cell disease (pink).

Image courtesy of Eye of Science/SPL.

Institute News

Science in Pictures

AuthorCommunications
Date

March 9, 2026

Colorized scanning electron micrograph of human lung tissue, depicting alveoli and bronchus. Lung alveoli are tiny, grape-like sacs, numbering in the millions, where essential gas exchange (oxygen/carbon dioxide) occurs. The bronchus is a major airway that branches from the trachea to conduct air into the lungs.

Image courtesy of Dennis Kunkel/SPL.

Institute News

Jimmy Massenet selected for Science in Motion Travel Award

AuthorCommunications
Date

March 3, 2026

The Sanford Burnham Prebys Center for Cardiovascular and Muscular Diseases recently announced that Jimmy Massenet, PhD, is a recipient of a 2026 Science in Motion Travel Award. 

Massenet, a postdoctoral associate in the lab of Pier Lorenzo Puri, MD, was selected to attend the 2026 Muscle Stem Cells and Regeneration Meeting held from July 19-24, 2026, in Victoria, the capital of the Canadian province of British Columbia. 

The goal of the Science in Motion Travel Award is to support conference participation for emerging researchers in labs with a primary affiliation in the Center for Cardiovascular and Muscular Diseases. 

Applications will open again on July 15, 2026.

Institute News

Science in Pictures

AuthorCommunications
Date

March 2, 2026

Colorized scanning electron microscope composition of human sperm traveling through a fallopian tube.

Image courtesy of Steve Gschmeissner/Getty.

Institute News

Women in Science Lecture series showcases public health and nutrition policy leader

AuthorGreg Calhoun
Date

February 23, 2026

The series highlights the groundbreaking work and unique perspectives of women leaders in the biomedical sciences

On February 11, 2026, Sanford Burnham Prebys Medical Discovery Institute hosted the second event in the Women in Science Lecture Series. The occasion opened with a presentation by Cheryl A.M. Anderson, PhD, MPH, MS, professor and dean of the Herbert Wertheim School of Public Health and Human Longevity Science at the University of California San Diego and director of the UCSD Center of Excellence in Health Promotion and Equity.

Anderson introduced attendees to some of the pivotal findings of her mentors studying the effects of nutrition on public health, including the landmark dietary approaches to stop hypertension (DASH) clinical trial. Because of the challenges in achieving significant heart disease prevention benefits outside of the controlled environments used in studies such as the DASH trial, Anderson was determined to explore other approaches.

“I put together this concept that instead of asking the individual to figure it all out from our dietary recommendations, maybe we could figure out how to have a healthy, sustainable food system,” said Anderson.

“I see a sustainable food system as one that maintains our ability to get lots and lots of nutrition and where you meet the current population’s needs without compromising what future generations might also need.”

In addition to discussing her scientific journey, Anderson provided insight into her experience serving with other experts to provide input into two different iterations of the federal government’s Dietary Guidelines for Americans. These guidelines from the Department of Health and Human Services and Department of Agriculture set the standards for food in federally funded programs such as public school and day care lunches as well as the Women, Infants and Children (WIC) special supplemental nutrition program. Anderson shared her experience working collaboratively to provide science-based counsel in an ecosystem that also contains political considerations such as the interests of industries involved in agriculture and food production.

Angela Liou, MD seated left and Cheryl A.M. Anderson, PhD, MPH, MS right

Anderson (at right) opened the event discussing her career journey focused on how to develop a healthy, sustainable food system. The event also featured a fireside chat and audience question-and-answer session with Anderson and Liou.

Lukas Chavez, PhD, MS, associate professor in the Cancer Genome and Epigenetics Program at Sanford Burnham Prebys and scientific director of the Pediatric Neuro-Oncology Molecular Tumor Board at Rady Children’s Institute for Genomic Medicine, then moderated a fireside chat and audience question-and-answer session with Anderson and Angela Liou, MD, physician-scientist and pediatric oncologist with a dual appointment at Rady Children’s Health and the Cancer Genome and Epigenetics Program at Sanford Burnham Prebys. Topics included: how new scientific insights are translated to reduce population-level health risks or guide care for children facing serious illnesses; how new technologies change the way you conduct research and deliver patient care; what can be done to ensure that scientific discoveries can be equitably accessed and lead to better outcomes for all; and what do future clinicians and scientists need in terms of skills, mindset and institutional support to succeed as public health researchers and physician-scientists.

The Women in Science Lecture Series, featuring quarterly events that are free and open to the public, is part of broader efforts at Sanford Burnham Prebys to foster an environment that nurtures the success of individuals from all backgrounds. The series is hosted by the Office of Workforce Engagement & Belonging and highlights the groundbreaking work and unique perspectives of women leaders in the biomedical sciences, while fostering mentorship and collaboration across the Torrey Pines Mesa.

Registration is open for the next event in the series on May 13, 2026.

Institute News

Science in Pictures

AuthorCommunications
Date

February 23, 2026

Carcinoma cells via fluorescence microscopy.

Image courtesy of Frederick Keeney, The Wistar Institute, Philadelphia.

Institute News

Science in Pictures

AuthorCommunications
Date

February 16, 2026

Mouse brain vasculature, as imaged by light sheet fluorescence microscopy.

Image courtesy of Ali Erturk, Munich, Germany.