Speakers
Shruti Bhatt, PhD
Assistant Professor
Emory University
David Chen, PhD
Associate Professor
Department of Systems Biology Department of Neurodegenerative Diseases
City of Hope
Adrienne Dorrance, PhD
Associate Professor
Experimental Therapeutics
Huntsman Cancer Institute
University of Utah
Derek Janssens, PhD
Assistant Professor
Department of Epigenetics
Van Andel Institute
Steve Lane
Professor, Group Leader
Gordon & Jessie Gilmour Leukaemia Research Laboratory
QIMR Berghofer
Medical Research Institute
Australia
Akihiko Yokoyama
Team Leader
Tsuruoka Metabolomics Laboratory
National Cancer Center, Japan
Nan Zhu, PhD
Associate Professor
Synthetic Biology Group
J. Craig Venture Institute
Panelists
Kathrin M. Bernt, MD
Assistant Professor, Pediatrics (Oncology)
Attending Physician, Division of Pediatric Oncology
Children’s Hospital of Philadelphia
Marina Konopleva, MD
Director, Leukemia Program
Co-Director, Translational Blood
Cancer Institute
Professor, Oncology and Molecular Pharmacology
Montefiore Einstein Comprehensive Cancer Center
Albert Einstein College of Medicine
Alexandra M. Stevens, MD, PhD
Associate Professor, Department of Pediatrics, Section of Hematology-Oncology
Baylor College of Medicine
Texas Children’s Hospital
Kira Gritsman, MD, PhD
Associate Professor, Departments of Oncology; Medicine; and Cell Biology
Co-Leader, Stem Cell & Cancer Biology Program
Montefiore Einstein Comprehensive Cancer Center
Betty and Sheldon Feinberg Senior Faculty Scholar in Cancer Research
Albert Einstein College of Medicine
Organized by
Ani Deshpande PhD
Peter D. Adams PhD
Agenda
| The Myeloid Precursor | |
|---|---|
| 9-9:10 | Opening Remarks Ani Deshpande, PhD Cancer Genome and Epigenetics Program Sanford Burnham Prebys |
| Session I Therapy Resistance | |
| 9:10-9:40 | How do Oncogenic Mutations Interact to Confer Chemotherapy Resistance in AML? Steven Lane QIMR Berghofer Medical Research Institute, Australia |
| 9:40-10:10 | COX4I1 controls Mitochondrial Homeostasis and Venetoclax Sensitivity in AML David Chen City of Hope, Duarte, CA |
| 10:10-10:30 | Targeting Non-Genetic Adaptations in AML Relapse Shruti Bhatt Emory University |
| 10:30-11:30 | Coffee with the Experts – Panel Discussion On AML Therapeutics Panelists Kathrin Bernt, MD Steve Lane Marina Konopleva, MD Alexandre Stevens, MD, PhD Kira Gritsman, MD, PhD |
| 11:30-12:30 | Lunch Break Pizza will be served |
| Session II Epigenetics | |
| 12:30-1 | Targeting SWI/SNF Chromatin Remodeling Complexes in AML Nan Zhu J. Craig Venture Institute, La Jolla |
| 1-1:30 | MLL Oncoproteins: Double Agents of Acute Leukemia Derek Janssens Van Andel Institute, Grand Rapids, MI |
| 1:30-2 | Roles of MOZ/MORF KAT and DOT1L KMT in Oncogenesis Akihiko Yokoyama National Cancer Center, Japan |
| 2-2:30 | The Bone Marrow Microenvironment in Hematologic Malignancy Adrienne Dorrance Huntsman Cancer Institute, Utah |
| 2:30-4 | Poster Session |