We’re bringing together leaders in cancer research.
Speaker
Alison E. Ringel, PhD
Assistant Professor
Department of Biology
Massachusetts Institute of Technology and Ragon Institute
“Metabolic Circuits Linking Lipid Metabolism to T Cell Immunity”
Lipid metabolism is disrupted at many levels in the tumor microenvironment, which reflects the interplay between systemic metabolic state and local cellular processes. For T cells, the impact of different lipid species on anti-tumor functionality remains incompletely understood, even though effector T cells take up a wide range of extracellular lipids. This talk will focus on new roles for lipid metabolites in regulating T cell activities involved in tumor control, and how this may be manipulated to improve anti-tumor immune responses.