About us

Learn how Sanford Burnham Prebys' innovative research leads to medical discoveries and drug therapies that benefit patients.
scientists at work

Leading the way

Sanford Burnham Prebys Medical Discovery Institute has deep expertise in fundamental biology and one of the most comprehensive drug discovery centers in the nonprofit world that accelerates the translation of our discoveries toward patient benefit.

40+ years

of pioneering research

Our mission

We conduct world-class collaborative research dedicated to finding cures for human disease, improving quality of life, and educating and training the next-generation of scientists, thus creating a legacy for its employees, partners, donors and community.

How we aim to improve human health

Sanford Burnham Prebys Medical Discovery Institute is dedicated to discovering the fundamental molecular causes of disease and devising the innovative therapies of tomorrow. The Institute takes a unique, collaborative approach to medical research and has established major research programs in cancer, neurodegeneration, diabetes, and infectious, inflammatory, and childhood diseases. The Institute is especially known for its world-class capabilities in stem cell research and drug discovery technologies.
Sanford Burnham Prebys is a U.S.-based, non-profit public benefit corporation based in San Diego (La Jolla), California.

Who we are

  • Sanford Burnham Prebys discoveries begin with our people – scientists, postdoctoral candidates, graduate students and support staff – who work collaboratively toward understanding the cause of disease and identifying new therapeutic approaches to improve human health.
  • As an independent, nonprofit institution, we focus on conducting biomedical research in cancer, neuroscience, immunolgy and rare children’s diseases.
  • The Institute is home to one of the most comprehensive drug discovery centers in the nonprofit world.
  • Our innovative approach to research underpins our strategic partnerships with the biotech and pharmaceutical industry.
  • We cultivate the next generation of biomedical scientists through our graduate and postdoctoral training programs.
Sanford Burnham Prebys employs more than 700 scientists and staff in San Diego (La Jolla), CA. We are widely recognized for our NCI-designated Cancer Center, the Conrad Prebys Center for Chemical Genomics and the Sanford Children’s Health Research Center.
Asset 1

Our approach to improving human health is built on three principles

Fundamental research

Our track record of pioneering research spans more than 40 years, and has produced breakthrough discoveries in cancer, neuroscience, immunology and rare children's diseases.

Learn More

Translational research

We operate one of the most advanced drug discovery centers in the world that leverages biomedical discoveries to develop prototype drugs.

Learn More

Education and training

We are committed to education and training the next generation of scientific leaders to ensure our legacy continues.

Learn More

Fact sheet

Sanford Burnham Prebys fact sheet

Download Fact Sheet

 


Publications

Improving drug discovery using image-based multiparametric analysis of the epigenetic landscape.

Farhy C, Hariharan S, Ylanko J, Orozco L, Zeng FY, Pass I, Ugarte F, Forsberg EC, Huang CT, Andrews DW, Terskikh AV

Elife 2019 Oct 22 ;8

Senescent human melanocytes drive skin ageing via paracrine telomere dysfunction.

Victorelli S, Lagnado A, Halim J, Moore W, Talbot D, Barrett K, Chapman J, Birch J, Ogrodnik M, Meves A, Pawlikowski JS, Jurk D, Adams PD, van Heemst D, Beekman M, Slagboom PE, Gunn DA, Passos JF

EMBO J 2019 Oct 21 ;:e101982

LPA<sub>1/3</sub> overactivation induces neonatal posthemorrhagic hydrocephalus through ependymal loss and ciliary dysfunction.

Lummis NC, Sánchez-Pavón P, Kennedy G, Frantz AJ, Kihara Y, Blaho VA, Chun J

Sci Adv 2019 Oct ;5(10):eaax2011

Cross Talk between eIF2α and eEF2 Phosphorylation Pathways Optimizes Translational Arrest in Response to Oxidative Stress.

Sanchez M, Lin Y, Yang CC, McQuary P, Rosa Campos A, Aza Blanc P, Wolf DA

iScience 2019 Sep 26 ;20:466-480

Macrophages fine tune satellite cell fate in dystrophic skeletal muscle of mdx mice.

Madaro L, Torcinaro A, De Bardi M, Contino FF, Pelizzola M, Diaferia GR, Imeneo G, Bouchè M, Puri PL, De Santa F

PLoS Genet 2019 Oct 18 ;15(10):e1008408

Model System Identification of Novel Congenital Heart Disease Gene Candidates: focus on RPL13.

Schroeder AM, Allahyari M, Vogler G, Missinato MA, Nielsen T, Yu MS, Theis JL, Larsen LA, Goyal P, Rosenfeld J, Nelson TJ, Olson TM, Colas AR, Grossfeld P, Bodmer R

Hum Mol Genet 2019 Oct 18 ;

Show All Publications