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SBP supporters Dr. Tom and Cindy Goodman host SBP’s postdocs for the holidays

AuthorHelen I. Hwang
Date

December 9, 2016

For the last ten years, Cindy and Dr. Tom Goodman have a tradition of inviting Fishman Fund winners, past and present, for a holiday celebration. “It’s a delight to see everyone in a social setting – listening, learning and sharing.” Conversations range from the latest and greatest on melanoma research to cultural discussions about what Thanksgiving is about.

The Goodmans have been supporters of Sanford Burnham Prebys Medical Discovery Institute (SBP) and the Fishman Fund for the last decade or so. Every year, they’ve invited the winners of the Fishman Fund to their own home to share a holiday dinner. Cindy Goodman’s family always had a tradition of having students over for big meals when she was growing up in Ohio. She wanted to continue the tradition here with SBP’s community.

The Fishman Fund provides funding for exceptional postdoctoral researchers with a Fishman Fund Fellowship and Fishman Fund Career Development Awards. Founded in 2001, the Fishman Fund was established by SBP supporters Mary Bradley and Reena Horowitz, to honor the Fishmans. In 2010, Jeanne Jones became the co-founder designee. SBP introduced the Fishman Fund Awards in honor of the Institute’s founders, Dr. William and Lillian Fishman. So far, the Fishman Fund has funded over 55 postdoctoral researchers.

Recently, the families of four Fishman Fund recipients went to the Goodmans’ home to share Thanksgiving dinner. Fishman Fund awardees Stefan Grotegut, Melanie Hoefer, Petrus de Jong, Bernhard Lechtenberg and Jia (Zack) Shen all enjoyed a holiday celebration with the Goodmans. Former Fishman Fund winner Karthik Bodhinathan also called from the Boston area, where he now works for a pharmaceutical company, after spending six holidays with the Goodmans.  In fact, they’ve grown so close that they met Bodhinathan’s sister on a trip to Singapore.

The appreciation we feel “magnifies in unexpected ways,” says Cindy. This year, there were 16 people in their home, including children, ranging from age 1 to 8 years old. The Goodmans made turkey, potatoes and cranberry sauce for some guests who’ve never enjoyed such a feast before.

For Shen and his family, it was their first American Thanksgiving and he wasn’t quite sure what to expect. “We really enjoyed the fantastic Thanksgiving dinner at Cindy and Tom’s home. The house was so cozy. Cindy and Tom just treated us like family members. During the dinner, we talked about life in San Diego, my plans for the near future and the funny things about my baby Olivia. Also, we had nice conversations with the other winners’ families. And all of us gave our thanks to Goodman family. It was a wonderful evening!”

“I would be delighted if others opened their houses and hearts to one student or family,” says Cindy Goodman. Their experiences have been so delightful that she hopes someone else will also gain from the gift of sharing as the Goodmans have benefitted for the last decade.

For more information about the Fishman Fund, click here.

Institute News

Meet the 2016 Fishman Fund awardees

AuthorHelen I. Hwang
Date

September 16, 2016

When Joana Borlido, PhD, got the call that she won the inaugural Fishman Fund Fellowship late on a Friday afternoon, she called her parents, who had been waiting up past midnight in her native Portugal to find out if she had won the prestigious two-year postdoctoral fellowship along with a $5,000 career-development cash grant.

After all, her mother, a science teacher, had inspired Borlido to go into science by bringing home props of human body parts and subscribing to an immunology comic series. Yes, those biology cartoons do exist.

On September 15, the Fishman Fund ceremony honored Borlido and Fishman Fund Career Development recipients Bernhard Lechtenberg, PhD, and Jia (Zack) Shen, PhD

In celebration of SBP’s 40th anniversary, the significance of the Fishman Fund has been elevated with the addition of a two-year postdoctoral award called the Fishman Fund Fellowship. The Fishman Fund Fellowship is an incredible award that not only compensates exceptional postdocs at a higher income level than a typical fellowship, but also comes with a one-time $5,000 flexible career-development award, which they can use to further their professional endeavors. The established Fishman Fund Career Development awards of $10,000 will continue to be awarded as well.

Since the Fishman Fund’s inception in 2001, the Fishman Fund has grown from $1,500 cash awards. It was first established by Horowitz and Mary Bradley in honor of founders Dr. William and Lillian Fishman. In 2010, Jeanne Jones became the co-founder designee.

During the ceremony, Fishman Fund co-founder Reena Horowitz discussed the importance of supporting “the next generation of biomedical trailblazers.” She also said that the “Fishmans believed passionately in cultivating early-stage scientific talent. They knew that young investigators must focus intently on honing research skills and gaining professional experience.” Horowitz also took a moment to honor friends and supporters who have passed: Mary Bradley, Erna Viterbi, Pauline Foster, and Conrad Prebys.

Nina Fishman, daughter of SBP founders Dr. William and Lillian Fishman, read from a speech her father gave at the Institute. He said, “Each is encouraged to develop original ideas, which can be tested experimentally and subsequently qualify for grant support. Together we have the ‘critical mass’ of intellectuals and skills to accelerate progress in sciences.” She added that the Institute has demonstrated that a “relatively small but highly focused group can provide a nucleus where the whole is greater than the sum of its parts.”

Past winner Petrus de Jong, MD, PhD, shared how the Fishman Fund has boosted his career. With the grant, de Jong attended a drug delivery systems symposium with biotech entrepreneurs, participated in a research symposium in pancreatic cancer and received tailored career advice from senior scientists. “These events have been crucial for my personal career development, which would not have been possible without the Fishman Fund Award,” he said.

Fishman Fund Fellowship Awardee:

Joana Borlido, PhD, explores the mechanisms through which the channels that connect the cell nucleus (where the genome is stored) affect the immune system. She works in the laboratory of Maximiliano D’Angelo, PhDHer work will help elucidate the molecular basis for the onset and development of leukemia.

She completed her PhD in Oncology at the University of Cambridge in the U.K. and her BS in Biology at the University of Porto in Portugal.

If Borlido is not in the lab, she can usually be found playing foosball, which she admits she would play during all her free time if she could.

Fishman Fund Career Development Recipients:

Bernhard Lechtenberg, PhD, studies cellular signaling networks in normal human physiology and diseases in the laboratory of Stefan Riedl, PhDLechtenberg uses protein X-ray crystallography to study diseases such as cancer and ALS (Lou Gehrig’s disease). He received his BS and MS from the University of Luebeck in Germany and his PhD from the University of Cambridge in the U.K.

In his spare time, he and his wife Anne Hempel, also a SBP postdoc, participate in Ragnar Relay races, in which a team runs nonstop day and night to complete a course of almost 200 miles.

Jia (Zack) Shen, PhD, develops functional screens of for drugs that inhibit ubiquitin ligases (enzymes that tag proteins with a small protein called ubiquitin). Such drugs, alone and in combination with current chemotherapies, are considered important advances in the therapy of breast cancer patients. Shen works in the laboratory of Charles Spruck, PhD, and received his BS from Zhejiang Sci-Tech University and his PhD from the Chinese Academy of Sciences.

He and his wife love taking their 6-month-old daughter Olivia for walks in San Diego. Shen also plays soccer twice a week with a team at the Salk Institute.

With the generous support of the Fishman Fund, this stellar group of postdocs will benefit tremendously from well-earned rewards for their hard work and vision for “Science Benefiting Patients.”

Institute News

Symposium brings leaders in tumor immunology to SBP

Authorjmoore
Date

March 21, 2016

SBP’s La Jolla campus recently hosted a one-day conference on Cancer Immunology and the Tumor Microenvironment, one of the hottest topics in cancer research. The symposium on March 17 attracted approximately 160 attendees from across the La Jolla biomedical research mesa.

The symposium was organized by Carl Ware, PhD and Robert Rickert, PhD, directors of the Inflammatory and Infectious Disease Center and the Tumor Microenvironment and Cancer Immunology Program, respectively. They planned a scientific agenda that covered diverse aspects of research on harnessing the immune system to treat cancer, from improving current immunotherapies to identifying new immunological targets. Talks were given by prestigious scientists including:

Two SBP researchers also presented. Linda Bradley, PhD, professor in the Immunity and Pathogenesis Program, discussed her work on the immune cell surface protein PSGL-1, showing that it regulates PD-1, a so-called “immune checkpoint.” PD-1 is found on T cells and normally acts as on “off switch” to keep the immune system from attacking cells in the body. PD-1 regulators are a new approach to treating cancer that work by unleashing cytotoxic T cells to kill cancer cells.

 

Adam Godzik, PhD, professor and director of the Bioinformatics and Structural Biology Program, spoke about using bioinformatic analyses to search for new cancer drivers related to the immune response. Cancer drivers are genes that, when altered, are responsible for cancer progression. Combining cancer mutation and protein structure databases, his team has identified many genes involved in immune recognition of tumors.

Institute News

Upcoming symposium: Cancer Immunology and the Tumor Microenvironment

Authorjmoore
Date

March 10, 2016

On March 17, SBP La Jolla is hosting a symposium on the interactions between the immune system and tumors, including how they can be leveraged for cancer treatment. The symposium is organized by Carl Ware, PhD and Robert Rickert, PhD, the directors of the Inflammatory and Infectious Disease Center and the Tumor Microenvironment and Cancer Immunology Program, respectively, and features presentations by leaders in the field:

Crystal Mackall, MDStanford University

Yang-Xin Fu, MD, PhDUT Southwestern

Mikala Egeblad, PhDCold Spring Harbor Laboratory

Linda Bradley, PhDSanford Burnham Prebys Medical Discovery Institute

Jose Conejo-Garcia, MD, PhDWistar Institute

Jonathan Powell, MDJohns Hopkins School of Medicine

Shannon Turley, PhDGenentech

Karen Willard-Gallo, PhDInstitut Jules Bordet – Belgium

Sandip Patel, MDUC San Diego

Adam Godzik, PhDSanford Burnham Prebys Medical Discovery Institute

The symposium will be held from 9-4:30 in Fishman Auditorium (overflow seating in the Building 12 auditorium), with a reception to follow. If you plan to attend, please register here.

Institute News

SBP’s 37th Annual Symposium: Aging and Regeneration

Authorsgammon
Date

November 3, 2015

On Friday, October 30, more 350 people came to SBP’s 37th Annual Symposium to hear leading scientists present their latest research on aging and regeneration.  The presenters, listed here, provided valuable insight into the latest studies on what causes aging, and strategies to repair injuries, prolong life, and prevent diseases.  The event was hosted by (from left to right): Rolf Bodmer, PhD, Malene Hansen, PhD, (in bee costume for Halloween) Alexey Terskikh, PhD

 

organizers-symposium-beaker

Many congratulations to Esther Minotti for successfully organizing the event!

symposium-photo-beaker

And many thanks to the Glenn Foundation for Medical Research for their support.

Institute News

Join us for the third annual cancer center open house – June 11

Authorrbruni
Date

April 30, 2015

Sanford-Burnham’s NCI-designated Cancer Center and the Cancer Center’s Community Advisory Board will host the third annual Cancer Center open house for cancer survivors, their families and friends, and research advocates on June 11 at 4:30 p.m. in La Jolla, Calif. The open house, titled “The Science Behind Immunotherapy,” will focus on revealing the latest discoveries and breakthroughs from our cancer center’s laboratories on harnessing the body’s own immune system to treat cancer. Continue reading “Join us for the third annual cancer center open house – June 11”

Institute News

Sanford-Burnham presents at the 2014 Society for Neurosience Meeting

Authorsgammon
Date

November 13, 2014

The Society for Neuroscience’s 44th annual meeting is the premier venue for neuroscientists to present emerging science, learn from experts, forge collaborations, and learn about new technologies and tools. Sanford-Burnham has several dynamic research programs in neuroscience, and below are our presentations scheduled for this year’s event. Continue reading “Sanford-Burnham presents at the 2014 Society for Neurosience Meeting”