Freeze Laboratory
Research
Dr. Freeze joined the faculty of the Sanford Burnham Prebys Medical Discovery Institute in 1988 and served as the Director of the Glycobiology and Carbohydrate Chemistry Program from 2000-2008. He is currently the Director of the Institute’s Human Genetics Program. His work focuses on pathology resulting from faulty glycos-ylation, the process of adding sugar chains to proteins and lipids. Carbohydrates are required for proper secretion and targeting of thousands of proteins, an often overlooked fact of biology.
He is driven by the search for novel therapeutics to treat patients with mutations leading to glycosylation defects called Congenital Disorders of Glycosylation or CDGs. We invite you to learn about the children with CDGs, read their stories, and meet the researchers seeking a cure for their disorders.
People
Bobby Ng BSc
- Staff Scientist
Jamie Smolin BSc
- Research Assistant
Zinia Dsouza PhD
- Postdoctoral Associate
Sonal Mahajan Puri PhD
- Postdoctoral Associate
Marwa Danish
- Lab Assistant
News
Events
- Rare Disease Day Symposium & CDG Scientific and Family Conference Congenital Disorders of Glycosylation: Models and Therapy | March 2024
- Inaugural Sanford Children’s Health Research Center Scientific Symposium Children’s Diseases: Models and Therapy | April 2023
- Rare Disease Day Symposium & CDG/NGLY1 Family Conference February 2022
- Rare Disease Day Symposium & CDG Family Conference: Congenital Disorders of Glycosylation Congenital Disorders of Glycosylation | February 2020
- 10th Annual Rare Disease Day Symposium Rare Bone Disorders and Tumors: New Frontiers of Translational Research | February 2019
- 9th Annual Rare Disease Day Symposium & CDG Family Conference Congenital Disorders of Glycosylation and Deglycosylation | February 2018
- 7th Annual Rare Disease Day Symposium Human Glycosylation Disorders | February 2016
- 6th Annual Rare Disease Day Symposium Treating Disease with Sugars | February 2015
- 5th Annual Rare Disease Day Symposium ERAD Defects in the Cytoplasm: The NGLY1 Story | February 2014
- 3rd Annual Rare Disease Day Symposium Identifying and Treating Rare Disorders | February 2012
- 2nd Annual Rare Disease Day Symposium February 2011
Videos
Select Publications
Showing 3 of 3Employment
If you are interested in a position in the Freeze Lab, please contact Dr. Freeze for information about possible openings, or visit Current Openings.
Contact
The Freeze Laboratory
Hudson Freeze, Ph.D.
Professor and Principal Investigator
Director, Human Genetics Program
Sanford Children’s Health Research Center
Phone: (858) 646-3142
Fax: (858) 795-5381
CDG Testing
To inquire about CDG testing for yourself or a loved one, please email Bobby Ng.
Student Volunteer/Internship Positions
For information about student volunteer/internship positions in the Freeze Lab, please contact Sinead King.
Charitable Donations
If you are interested in supporting Dr. Freeze’s work with a gift, please contact giving@sbpdiscovery.org, and you will be contacted by a member of the Philanthropy team.