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Women in Science event at Sanford Burnham Prebys examines how female faculty members navigate research careers

AuthorGreg Calhoun
Date

August 19, 2024

Four panelists at different career stages shared insights and answered audience questions

Sanford Burnham Prebys held a Women in Science event on Monday, August 12, 2024. The session was in Fishman Auditorium on the Institute’s campus and focused on how female faculty members at different career stages have navigated their professional journeys in academia and the life sciences. 

Eric Wang,  PhD, an assistant professor in the Cancer Molecular Therapeutics Program at Sanford Burnham Prebys and co-chair of the Education and Training Diversity, Equity and Inclusion (DEI) Committee, opened the event and introduced the moderator, Shanshan Yin, PhD, a postdoctoral associate working in the lab of Peter D. Adams, PhD, and four panelists from Sanford Burnham Prebys: 

  • Caroline Kumsta, PhD, an assistant professor in the Development, Aging and Regeneration Program and associate dean of Student Affairs of the Graduate School of Biomedical Sciences 
  • Alessandra Sacco, PhD, the director of the Development, Aging and Regeneration Program and dean of the Graduate School of Biomedical Sciences 

Shanshan Yin, PhD, is a postdoctoral associate working in the lab of Peter D. Adams, PhD. She was the panel discussion moderator.

Work and life balance 

Yin asked the panelists to discuss how they balance their work and personal lives, and what strategies they use to restore their energy levels and maintain a positive mindset. 

“I had to learn to manage my schedule, rather than letting it manage me,” said Kumsta. “I’ve gained a greater appreciation for stepping away from problems, and I often find that I come up with new solutions during or after hiking or working out, instead of by just working more and more.” 

“Because I am setting up a new lab, it feels like I am working even more than I did as a postdoctoral fellow,” said Sun. “My persistence, curiosity and interest in the scientific process are the key drivers that are helping me as the lab gets up to speed.” 

Caregiving 

Yin followed this conversation by requesting that the panelists comment on the factors of childcare and family obligations throughout the careers of female faculty members. 

“The childcare system for working parents in the U.S. leaves a lot of room for improvement,” said Bradley. “This has not improved through the course of my career, and it is something we think about a lot within the Postdoctoral Training Advisory Group as we discuss ways to improve the experience of postdoctoral fellows at the institute.” 

Panelist Xueqin (Sherine) Sun, PhD, is an assistant professor in the Cancer Genome and Epigenetics Program.

“It can be hard to feel less productive as a scientist after having kids,” said Sun. “This is something we each have to navigate and there are no easy answers.” 

Audience questions 

Yin welcomed audience members to ask the panelists additional questions. 

Sacco fielded a question about the balancing act of working long hours for short-term gain versus the increased risk of burnout. She said, “For me, this has really happened in phases. Some parts of certain experiments or application cycles require extra effort, and you have to learn when you can pull back and have a more balanced schedule.” 

Kumsta answered a question about unrealistic expectations for postdoctoral fellows. She said, “I encourage every postdoc and principal investigator to have open and honest conversations about expectations for working hours, vacation time and weekend emails, among other topics. That won’t fix everything, but it will prevent a lot of uncertainty and build a foundation for addressing issues.” 

The panelists had noted the strong representation of male scientists and staff members in the audience. Sacco responded to a question about what male scientists could do better to improve the environment for women in the field. She said, “We should all recognize our own biases, minimize their impact when making decisions, and be good listeners to other scientists’ needs.”      

Gender and academic rank 

The event closed with a conversation about gender disparities in academic ranks at research and higher education institutions. The panelists focused on the attrition than can occur after the end of postdoctoral fellowships as a major challenge for retaining women in academic science.  

Kumsta explored some potential solutions that funders and institutions could consider. She said, “An extra year of funding for early-career female scientists and an extra year on the tenure clock may help us retain women and support their promotion from junior faculty positions. We also need to find ways to reward the extra administrative service that many female faculty members are asked to give on faculty committees.” 

Caroline Kumsta, PhD

Panelist Caroline Kumsta, PhD, is an assistant professor in the Development, Aging and Regeneration Program and associate dean of Student Affairs of the Graduate School of Biomedical Sciences.

“I think certain things are getting better, but we need to do even more to retain women in the field,” said Sun. “The National Institutes of Health allowing time and budget for childcare costs in training grants was an important step.” 

“Today’s event reminds us of the importance of speaking up,” said Sacco. “We can articulate and share our vision for a better tomorrow and work together to achieve it.” 

The Women in Science event was hosted by the Education and Training DEI Committee at Sanford Burnham Prebys and supported by the Institute’s Diversity, Equity, Inclusion and Belonging (DEIB) Council and DEIB program manager, Lauren Mitchell.  

Institute News

Pride flag flies proudly at Sanford Burnham Prebys 

AuthorGreg Calhoun
Date

June 11, 2024

The Institute marked Pride month by ceremonially raising the Pride flag and discussing progress toward inclusion in the scientific community

Sanford Burnham Prebys recognized the beginning of Pride month with a Pride flag-raising event on Friday, June 7, 2024. The gathering included an opportunity for speakers in a variety of roles throughout the Institute to share comments on the meaning of the Pride flag in their lives and careers. 

David Brenner, MD, president, CEO and Donald Bren Chief Executive Chair at Sanford Burnham Prebys, opened the ceremony, saying, “I’m very proud of everyone for working together to make this a welcoming community.” 

Luca Caputo

Luca Caputo, PhD, postdoctoral associate in the lab of Lorenzo Puri, MD, discussed the mission of the Queer Science Society, which was founded to create a safe space for postdoctoral fellows and other scholars in San Diego. He added, “I’m happy to be here in this inclusive environment.” 

Patrick Kearney, PhD, director of medicinal chemistry in the Conrad Prebys Center for Chemical Genomics, added, “After I joined the Institute last year and saw the Pride flag flying for the first time, I was incredibly moved. It was the first time I’d seen this happen in 40 years as a scientist. While it may seem simple, it is far from trivial, and it tells me that things are different here.” 

Luca Caputo, PhD, postdoctoral associate in the lab of Lorenzo Puri, MD, discussed the mission of the Queer Science Society, which was founded to create a safe space for postdoctoral fellows and other scholars in San Diego. He added, “I’m happy to be here in this inclusive environment.” 

Patrick Kearney, PhD, director of medicinal chemistry in the Conrad Prebys Center for Chemical Genomics, added, “After I joined the Institute last year and saw the Pride flag flying for the first time, I was incredibly moved. It was the first time I’d seen this happen in 40 years as a scientist. While it may seem simple, it is far from trivial, and it tells me that things are different here.” 

Allessandra Cecchini

The Pride flag-raising event was planned by the Institute’s Diversity, Equity, Inclusion and Belonging (DEIB) Council. Lauren Mitchell, MS, program manager for DEIB, expressed gratitude for the meaningful contributions of the volunteers and speakers, as well as the many participants that attended and showed support for DEIB at the Institute.

Pride flag raising

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Institute News

Speaking of International Day of Women and Girls in Science

AuthorScott LaFee
Date

February 7, 2024

Designated by the United Nations, the 9th International Day of Women and Girls in Science is Sunday, February 11, preceded by two days of meetings, presentations and outreach among global leaders, with a focus on women scientific leadership in sustainable development.

The real work, of course, is what happens afterward. Women continue to be underrepresented in the science, technology, engineering and mathematics (STEM) workforce. In 2021, according to the National Center for Science and Engineering Statistics, 65% of STEM jobs in the United States were held by men, 35% by women. Less than 30% of researchers worldwide are women.

These numbers have long held sway, both in academia and industry. There has been progress, to be sure, but it has been slow and uneven, hindered by stereotypes and biases, a dearth of role models, educational differences and opportunities and sheer inertia. The hurdles to equity and equality are deep and ingrained.

Every female scientist has stories about their own efforts and struggles. We asked scientists at Sanford Burnham Prebys to recount some of theirs, the lessons learned and the challenges yet to be overcome.

A fighting chance

My personal experience can testify to the importance of appreciation of diversity.

As an international scholar, it was not always easy to navigate an entirely new culture. I remember my first few months in America when going to a restaurant felt like a small adventure. Now I look back to those days with fondness and gratitude because my mentor and colleagues showed me what an inclusive community means to a newcomer.

They encouraged my expression, valued my input and always waited with great patience when I needed a second or two to fetch a perfect word for the moment. It was their kindness that helped me through the initial adjustment period.

And then one day, I found the sense of belonging in a roaring ballpark with my lab mates around me, rooting for Giants. I am grateful that I was shown how “diversity” is done because that is exactly how I aspire to build a team in my future lab, a team where uniqueness is not only accepted but even celebrated so everyone can be at ease as themselves and feels free to explore and express no matter where they are from and what they believe.

While it is important to level the playing field for everyone, sometimes it will not suffice for a disadvantaged group until we vigorously advocate for their rights. As a woman scientist, it pains me that I have witnessed over the years so many brilliant young women who had to stop chasing their dreams at one point or another. They let go of their passion and settled for less ambitious career paths for various reasons: lack of mentorship, family responsibilities and even the pressure of conforming to social norms.

I know how hard it is to achieve success in the highly competitive realm of scientific pursuit while managing a functional family because I am too a mother of two young children. Our society asks women to juggle too many balls. It is no wonder that far fewer
women reach the promised land of professorship when roughly equal numbers of students of
both genders started out on this journey.

Shengjie Feng, PhD

Shengjie Feng, PhD
Assistant Professor
Degenerative Diseases Program

I consider it rare fortune that I have been blessed with constant guidance from mentors and unwavering support from family. It will be my mission to pass on this blessing to all the women I have the honor to work with in the future. A fighting chance is all they ask, and I will strive to be the helping hand that delivers that chance.

Mentors make a difference

Even though gender inequities in STEM are slowly improving, we still have a lot of work to do. Several studies have shown that among early career investigators, women experience a one-to-two delay in getting their first grants funded, publish fewer high-impact papers and get credited and cited less frequently for their work, as compared to men. I believe that creating awareness and building a supportive network of mentors and peers is extremely important to navigate and overcome the challenges we face in science.

I have always been fascinated by the complex mechanisms underlying disease, and specifically cancer. I was the first woman in my family to attend university and to pursue a PhD degree in the biomedical sciences.

With few women in leading academic positions that could serve as a role model, I found it difficult to believe that I could someday be successful as a scientist. Fortunately, over the past years I have had the opportunity to work with some incredible female scientists who helped me along the way.

During my master’s program at Utrecht University, I secured an internship in the laboratory of the late-Professor Zena Werb at University of California San Francisco. She had an incredible track record of mentoring early career researchers and was a big advocate for (young) women in science.

For my graduate training, I joined the lab of Professor Karin de Visser at the Netherlands Cancer Institute in Amsterdam. Karin is an incredibly smart and determined principal investigator who taught me to be resilient and persistent, and the importance of always following the data. The mentorship and support of these remarkable women has been instrumental in the decisions I have made to date in my career, and I am grateful for the opportunity to have trained under them.

Kelly Kersten, PhD

Kelly Kersten, PhD
Assistant Professor
Cancer Metabolism and Microenvironment Program

We all need some support and encouragement to excel in our scientific journey. It’s never too early to start building your network of mentors, peers and sponsors to support you along the way.

We’re still a minority

During my PhD and postdoctoral training, I have been lucky to have two amazing female scientists as mentors, who made it seem easy to be successful in science. The reality however is that female scientists get less lab space, have a longer path to their first independent research grant and have a more extended review process for their publications than their male peers.

To achieve equitable treatment and full inclusion of women in science, we have to constantly examine and dismantle the barriers that create these disparities. At Sanford Burnham Prebys, we have started to work toward a more welcoming environment for everyone, including women.

The truth is, however, that we’re still a minority here, and we, as women in science, still have to push for fairer policies and to make sure our voices are heard and valued. Personally, I am involved in outreach programs to get young girls excited about science. Seeing their excitement when they learn something new in the lab reminds me why this is so important, and I get excited when I see the next generation of girls who can see themselves as scientists without a second thought.

Caroline Kumsta, PhD

Caroline Kumsta, PhD
Assistant Professor
Development, Aging and Regeneration Program

Note: On February 14, there will be a roundtable discussion on the topic of women and girls in science from 9:30 a.m. to 10:30 a.m. in Fishman Auditorium. Coffee, pastries and fruit will be served. Click here to RSVP.

Institute News

San Diego Pride is this week. We asked: Why are LGBTQ+ people the “invisible minority” in STEM?

AuthorMiles Martin
Date

June 22, 2023

Conversations around diversity and inclusion are abundant in academic institutions, but one group in particular—the LGBTQ+ community—is frequently left out of those conversations.

June is LGBT+ Pride month, but San Diego has made it a local tradition to continue the celebration into July, when the city hosts its annual Pride Festival. This year’s San Diego Pride Festival will be held July 15-16. Pride celebrations around the world give people and institutions alike the opportunity to reflect on the unique struggles of the LGBTQ+ community and consider how we can support these individuals to the benefit of all.

To learn more about the struggles of LGBTQ+ people in the scientific community, we spoke to Sanford Burnham Prebys postdoctoral associate Luca Caputo, PhD Caputo is the cofounder of Queer Science Society San Diego, whose mission is to raise awareness of the concerns of queer scholars in STEM. They are a frequent speaker on LGBTQ+ issues in STEM, most recently at the Fleet Science Center in Balboa Park, where they are included in their New Science exhibition. Caputo is also involved in DEI initiatives here at the Institute, where they helped spearhead our first-ever Pride flag raising last year. 

Why is LGBTQ+ considered the “invisible minority” in STEM? 

The reason why the LGBTQ+ community is an invisible minority is not because there are no queer scientists or STEM professionals. Rather, it’s because there’s a huge lack of data about queer representation in the scientific community. This community has historically not asked for this data, so queer people are not represented in reports and statistics about minority representation. This is not just a data problem—it can prevent LGBTQ+ people from feeling like they belong in STEM. 

Luca Caputo, PhD

Have you personally experienced this?

The lack of representation of queer scientists during my earlier studies had me questioning my belonging in STEM and academia, and the lack of data and discourse around these issues only made it worse. I was lucky and privileged to later encounter great mentors who made me feel welcome and appreciated for everything I am, not only for my pipetting skills. However, not everybody is so lucky.

What needs to happen to correct this problem?

Institutions that track demographic data for scientists and STEM students need to be more inclusive in their methods. This is slowly starting to change—one great example is that the National Science Foundation is finally including questions on sexuality, orientation and gender identity in its Survey of Earned Doctorates, but this is just one small step forward. 

There are still major societal problems affecting queer people in academia, such as unfair U.S. immigration laws that don’t acknowledge same-sex partnerships as marriages for visa purposes. These laws keep talent away from the U.S. or pose an unfair economic burden to same-sex couples, as they will need to travel abroad and navigate complex legislation to get married and be recognized. 

In the meantime, what can non-queer allies do to support the LGBTQ+ community in STEM?

One important thing is being responsive and listening to what members of the community have to say. An easy example is to normalize and respect the sharing of pronouns in email signatures and in Zoom meetings. This will help create a welcoming atmosphere and an environment that will allow LGBTQ+ individuals to safely come out and be confident and comfortable. 

On a more institutional level, many steps can be taken to make workplaces more welcoming, such as having all-gender-inclusive restrooms and honoring Pride months with concrete gestures, like holding Pride events. It’s also important not to wait for members of the LGBTQ+ community to ask for these gestures. These are all approaches that can be translated to being allies to any underrepresented group in STEM, not just the LGBTQ+ community.

How does being more inclusive benefit the scientific community as a whole?

It benefits the community in so many ways. For example, the amount of talent in the scientific community will increase exponentially. Having different point of views will increase our ability to find new cures for diseases and solutions to other real-world problems. Additionally, we have an ethical obligation to make the community inclusive and representative of the whole population, because most basic research is paid for by the entire public via taxes and charitable donations. Finally, increasing inclusivity will also improve the relationship between the scientific community and the general population, as marginalized communities will be able to see their needs and perspectives represented.

Institute News

Padres Pedal the Cause 2023: Team Sanford Burnham Prebys raises $50,000 for cancer research

AuthorMiles Martin
Date

March 20, 2023

Team Sanford Burnham Prebys hit the pavement this weekend for Padres Pedal the Cause, an annual fundraising event that invites participants to cycle, spin, run or walk to support local cancer research. The funds raised through each year’s race go to seed grants that fund collaborative cancer research projects in San Diego.

“Padres Pedal the Cause is a chance for the cancer community to come together and remember why collaboration is so important in cancer research,” says bike rider Ze’ev Ronai, PhD, director of the Institute’s NCI-designated Cancer Center. “Virtually all of us know somebody who has been impacted by cancer, including me. This is my fifth Padres Pedal the Cause, and every year I’m so proud to be part of our Institute’s team and help contribute to cancer research outside the lab.”

This year’s team was formidable: 56 employees and friends of the Institute signed up to either ride, run, or walk in the event. Team members came from all areas of the Institute, including faculty, staff scientists, administrative staff, postdocs, and even current and former members of the Institute’s Board of Trustees, such as Bill Gerhart and Steve Williams. Other notable names on this year’s team included longtime participants such as Professor Nicholas Cosford, PhD and James Short, associate director of Digital Communications and Design. 

“I’ve been with Padres Pedal the Cause since the very beginning, and it’s one of the highlights of my year,” says Short, who has helped lead the Institute’s team for the last 10 years.

The team also included some new members this year, such as Assistant Professor Lukas Chavez, PhD, and Director of Experimental Pharmacology Raghu Ramachandra, PhD, who both joined the Institute late last year. 

While Institute employees were well represented on this year’s team, there were also current some of the team’s top fundraisers had a different reason to join team Sanford Burnham Prebys. Kim McKewon is a longtime donor to the Institute and has been participating in Padres Pedal the Cause since its inception in 2013. This year she raised more than $6,000; and to date, she has raised more than $30,000. 

“I pedal for my husband, Ray, who is in remission from leukemia because of science and research, the very focus of the grants that are given from the fundraising that comes out of this event,” she writes in her website bio.

It’s not too late to support Team Sanford Burnham Prebys
To date, team Sanford Burnham Prebys has raised more than $300,000 through Padres Pedal the Cause since its inception in 2013. And while this year’s ride is over, there is always time to support local cancer research. The fundraising deadline for this year’s Padre’s Pedal the Cause is April 18, and 100% of every dollar raised goes toward lifesaving cancer research. Help team Sanford Burnham Prebys create a world without cancer.

Support Team Sanford Burnham Prebys

 

 

Institute News

Sanford Burnham Prebys celebrates one of its legends

AuthorMiles Martin
Date

March 8, 2023

In 2022, Distinguished Professor Emeritus Erkki Ruoslahti, MD, PhD, was awarded the Albert Lasker Basic Medical Research Award, the top American prize for biomedical research.

Ruoslahti was also among the first scientists to join the Institute in the late 1970s, where he completed this award-winning research. To celebrate Ruoslahti’s career and accomplishments, Sanford Burnham Prebys hosted a special lecture with the esteemed scientist as well as a celebratory reception afterward.

“Erkki’s illustrious career is one that keeps us all inspired—me, especially, as I follow in his footsteps in leading this Institute,” says David A. Brenner, MD, president and CEO of Sanford Burnham Prebys. “His Lasker Award win is so very much deserved. Not only does it recognize his outstanding influence in the field, but it also elevates the status of our Institute in the research community.”

Ruoslahti, who shares the award with Richard O. Hynes from the Massachusetts Institute of Technology, and Timothy A. Springer from Boston Children’s Hospital and Harvard Medical School, began his presentation with the research that led to his discovery of the integrins—proteins found on the surface of cells that helps them attach to, and communicate with, nearby cells and the extracellular matrix. 

Ruoslahti’s road to the discovery of integrins began at the University of Helsinki, where, along with his colleagues, he discovered fibronectin, a protein that helps surround, support and give structure to cells and tissues in the body. However, the biggest breakthroughs were yet to come.

Erkki Ruoslahti gives lecture to full a full auditorium

Ruoslahti gave his presentation to a packed house in Fishman Auditorium

“My research on fibronectin and the subsequent discovery of the integrins really got going in my first years at Sanford Burnham Prebys,” says Ruoslahti, who first joined the Institute in 1979, when it was known as the La Jolla Cancer Research Foundation.

The Ruoslahti research team discovered that a simple sequence of three amino acids, called RGD, within fibronectin, attaches directly to cells. They were then able to synthesize RGD and use it as a tool to discover the cell-surface receptors today known as the integrins. This seemingly small discovery created an entirely new subdiscipline of molecular biology.

“The Lasker Award is given for a fundamental discovery that opens up a new area of biomedical science. It is America’s top biomedical research award and is often referred to as ‘America’s Nobel,’” says Brenner. “This is a profound honor, one that is only given to those who have made the greatest impact in our field.”

In 1989, Ruoslahti became president and CEO of the Institute, a position he held until returning to full-time research in 2002. He became a Distinguished Professor Emeritus at Sanford Burnham Prebys in 2020. Ruoslahti has previously received the Japan Prize, the Gairdner Foundation International Award, the G.H.A. Clowes Memorial Award, and the Robert J. and Claire Pasarow Foundation Medical Research Award. He is also a Knight of the Order of the White Rose of Finland, a Commander of the Order of the Lion of Finland and is among the most cited scientists in the world.

Institute News

How community collaboration shapes leukemia research at Sanford Burnham Prebys

AuthorMiles Martin
Date

October 4, 2022

Since 2020, Todd and Rena Johnson, co-founders of the Luke Tatsu Johnson Foundation (LTJF), have helped fund the research of Associate Professor Ani Deshpande, PhD

But it all started with their son Luke. He had a very rare subtype of acute myeloid leukemia, one of the most difficult-to-treat cancers, and, sadly, he passed away from the disease in 2016. This inspired the Johnsons to become involved with fundraising and advocacy for cancer research.

“Our foundation started with a fundraising golf tournament to honor Luke, and that was about taking something so horrific and so horrible and finding a way to turn it into something positive,” says Rena. “If you can take that tragedy and put a positive spin on it, then everything around Luke and his name and his memory becomes positive.”

How “the stars and planets aligned” to bring the Johnsons to the Institute

In a remarkable coincidence, the Johnsons discovered on their first visit to the Institute that Deshpande’s research focuses on AF10 fusion AML, an extremely rare subtype of the disease that accounts for about 5 percent of cases. It’s also the subtype of AML that Luke had.

“It was a goosebumps-raising moment,” says Todd. “Once we visited Ani and saw his lab, we realized there was a lot more in common with our story and his research than we had realized before.”

“The stars and planets aligned and brought us to Ani,” adds Rena. 

Luke Tatsu Johnson

Luke Tatsu Johnson

As well as helping fund Deshpande’s research through LTJF and their partnership with the Rally! Foundation, the Johnsons are also on the Community Advisory Board (CAB) for the Institute’s Cancer Center, which advocates for cancer research by engaging the community. 

“The CAB does such a wonderful job of connecting the community with the scientists, and we’re so excited to be involved in that,” says Todd. “That’s fundamentally what we do as a foundation—we support the folks doing this work so that children and families down the road can have a different outcome from Luke’s.”
 

AML research “needs more support and needs more funding”

The Johnsons’ support helped the AML research team discover a new potential treatment for AML, which is currently in preclinical studies, after which they hope it will advance to clinical trials. The research team maintains that it would have been impossible to secure the NIH grants necessary to do these studies without the jump start given by the LTJF and the Rally! Foundation.

“We couldn’t do what we do without the Johnsons’ support,” says Deshpande. “We are so grateful to have them in our corner, and we’re confident that our work will help improve outcomes for kids like Luke down the line.”

Despite this progress, more research into AML and other leukemias is still needed. Leukemia is the most common cancer in children and teens. About 4,000 children are diagnosed with leukemia each year, and AML accounts for about a third of these cases.
 

Studying AML from all angles

To tackle this pressing problem, the Institute has established an AML disease team composed of researchers across labs and clinician partners. The team’s research falls into several large categories, including studying the genetics of AML, studying how the disease works in animal models and working to develop drugs that can target specific mutations associated with the disease, which are numerous. 

“AML has many different subtypes, so it’s been difficult for researchers to make major advances to treat all cases of AML,” says Deshpande, who co-leads the AML team with Professor Peter D. Adams, PhD “Most patients with AML are given the same treatments that have been used since the ’70s, which is why we want to look at AML from as many angles as possible.”

In addition to being difficult to treat, it is also challenging to get funding for AML research, particularly for the rarer subtypes. This makes the support of foundations such as LTJF even more vital to researchers like Deshpande. 

“This is exactly why AML research needs more support and needs more funding, because this is a much more difficult disease than other forms of leukemia,” says Todd. “Many patients don’t have positive outcomes, and the only way to turn that pendulum is to intensify our efforts and increase the amount of research being done.”

Institute News

One plant at a time: How Sanford Burnham Prebys is helping the monarch butterfly

AuthorMiles Martin
Date

August 9, 2022

Monarch butterflies are in trouble, and we’re doing something about it

To help protect the monarch butterfly, which was recently declared endangered, Sanford Burnham Prebys is planting milkweed on campus. Planting milkweed and other butterfly-friendly flowers along monarch migration routes is a key strategy to support this iconic California species and prevent further decline. 

“In the ’80s, we all took the butterflies for granted,” said Eva Engvall, PhD professor emerita at Sanford Burnham Prebys. Professor Engvall’s comments on the decline of the monarch were immortalized several years ago in a printed mural on campus. “Thirty years later, we never see them.”

The International Union for the Conservation of Nature (IUCN) recently added the monarch butterfly (Danaus plexippus) to its list of endangered species. The distinctive orange-and-black butterflies are a staple of Californian wildlife, but their numbers have drastically declined over the last 30 years.

Although monarchs are known for their heroic migration to Mexico and back each year, those that live west of the Rocky Mountains need not travel so far—many of their overwintering sites are located right here in California, with others scattered throughout West Coast states.

In the 1980s, when Sanford Burnham Prebys was known as the La Jolla Cancer Research Foundation, some of these resting sites could be found on our campus. Today, this is no longer the case.

Habitat destruction from agriculture and urban development, along with declining milkweed populations caused by drought and fire, have decimated the butterfly population. The IUCN estimates that the population of West Coast monarch butterflies has fallen by an estimated 99.9% between the 1980s and 2021.

“For some time, I thought they didn’t come to La Jolla because the area had been so developed,” said Engvall. “But this is apparently not the cause of the reduction in the number of butterflies, but rather the lack of the plant milkweed, which the larvae need to feed on.”

To combat this problem, the Institute has planted several milkweed plants along our on-campus walkways. Milkweed plants provide shelter and a place to lay eggs for adult butterflies, and they are the only plants that monarch caterpillars eat. Dozens of monarchs have already been spotted on the milkweed just outside Building 1. 

“They eat so fast that we may need to plant more at this rate,” says facilities director John Reed, who planted the milkweed last week. 

Monarch caterpillars feeding on milkweed plats

One caterpillar quickly became many on our on-campus milkweed plants

The milkweed planting is the latest in a series of steps the Institute has taken to help protect the environment and promote sustainability. Sanford Burnham Prebys has been recognized as a trailblazer in water conservation for its innovative water-saving landscaping, and the Institute also recently completed a sweeping round of solar energy upgrades.

“It’s great that our Institute is able to do our part to protect the environment, including these beautiful monarch butterflies,” adds Reed.

Institute News

Sanford Burnham Prebys celebrates 46 years of discoveries

AuthorMiles Martin
Date

July 27, 2022

Happy birthday, Sanford Burnham Prebys

Sanford Burnham Prebys recently hosted a celebration to honor the anniversary of the Institute’s founding. More than 200 scientists, students and staff gathered to commemorate 46 years of world-class biomedical research. 

“I’ve seen the Institute grow from just five employees to the more than 500 we have today,” said Institute Professor José Luis Millán, PhD, who emceed the event. Millán joined the Institute in 1977, just one year after its founding. “What is important for the Institute now, as we reach middle age, is to reflect on our successes as we move forward into the next decades of our life.”

Attendees enjoyed an all-you-can-eat ice cream truck and a prize raffle, where guests won Institute hats, mugs and other prizes. Longtime supporters of the Institute also spoke, including Malin Burnham, Nina Fishman, and Debbie Turner, partner of the late Conrad Prebys. The party closed with a recorded birthday song from Institute Professor Hudson Freeze, PhD

Burnham recounted how he met the Institute’s two other namesakes, T. Denny Sanford and Conrad Prebys, reflecting on how these chance meetings helped the Institute grow to become the world-class facility it is today. He also expressed his gratitude to the staff. 

“All of you are a part of the family, and that is what I’ve enjoyed as much as anything in my 40 years with this organization,” said Burnham during his comments. “I want to thank each and every one of you for being a part of this organization.”

Decades of discoveries
Sanford Burnham Prebys was founded on July 7, 1976, as the La Jolla Cancer Research Foundation. Since then, the Institute has established itself as a world leader in biomedical research, where scientists can work collaboratively to discover cures.

It all started when founder William Fishman, MD, PhD, left his post as professor, director and founder of the Tufts Cancer Research Center in Boston. He, along with wife and career partner, Lillian Fishman, moved west to San Diego with a $180,000 grant from the National Cancer Institute, which they used to start the La Jolla Cancer Research Foundation.

“[The Fishmans] were dedicated to the idea of pure science,” explains Nina Fishman, daughter of William and Lillian. Nina Fishman is a longtime supporter of Sanford Burnham Prebys, and she recently coauthored Development of a California Research Organization, a book chronicling the Institute’s history. “They wanted a place where scientists could focus on their work.”

At that time, the foundation consisted of five employees, a rented office space, and lab equipment pieced together from spare parts. Today, it is a world-class medical research institute with a graduate school and one of only seven NCI-designated basic cancer centers in the country.

“My parents were the founders of the past, but you are the founders of the future,” adds Fishman.

Institute News

Sanford Burnham Prebys raises flag for Pride Month

AuthorMiles Martin
Date

June 13, 2022

The ceremony featured speakers from the Institute and was the first formal LGTBQ+ Pride event to be held on campus.

Scientists and staff from across the Institute gathered to celebrate LGBTQ+ Pride at Sanford Burnham Prebys by attending a Pride flag raising ceremony. Our employees spoke to the importance of inclusion in STEM, and the Pride flag was hoisted from the main campus flagpole.

“By supporting LGBTQ+ and other underrepresented groups, institutions signal that they are open to different viewpoints and people, which is crucial,” says Luca Caputo, PhD, a postdoctoral fellow in the lab of Pier Lorenzo Puri, MD Caputo has been heavily involved in the Institute’s DEI initiatives, and he is also a co-founder of the Queer Science Society, an organization that raises awareness on issues facing LGBTQ+ scholars in STEM. 

“Having a celebration such as the Pride flag ceremony here at Sanford Burnham Prebys helps us support LGBTQ+ scientists at the Institute and beyond,” he adds. 

After an introduction by Alessandra Sacco, PhD, Caputo spoke about the importance of Pride Month and highlighted the need to promote inclusion and diversity in STEM. 

“This is just the first step in the right direction of making Sanford Burnham Prebys a truly inclusive campus and Institute,” he said during his remarks. “I and others on campus are going to hold [our Institute] accountable for numerous steps that are necessary to create a real welcoming and supportive environment, not just for queer scholars but for all underrepresented groups.”

In addition to these comments, Caputo shared his personal story as an LGBTQ+ scientist and briefly described the “invisible minority” phenomenon for LGBTQ+ scientists. This term refers to the fact that the LGBTQ+ community is often excluded from studies aimed at understanding diversity in STEM.

“The lack of inclusion in demographics has a profound effect on efforts to increase equity and inclusion for the LGBTQ+ community” says Caputo. “Many undergraduates do not know or have access to a single LGBTQ+ scientist.”

After Luca told his story, Professor Hudson Freeze, PhD spoke to the spirit of inclusion that Sanford Burnham Prebys was founded on. He also mused on the future of inclusion at the Institute.

“This [flag raising] is a good start, but it’s not the end – We have to keep this going,” Freeze said during his remarks. 

And while this was the first formal Pride event to be held at Sanford Burnham Prebys, it certainly will not be the last.

“Pride means freedom. Pride means hope that future generations of LGBTQ+ people won’t have any doubts about themselves and their worthiness to be in STEM,” says Caputo. “Supporting LGBTQ scientist is simply the right thing to do.”